Holo Transferrin

Description

Holo Transferrin
Catalog number: B2013720
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 25 mg
Molecular Weight or Concentration: 395
Supplied as: Serum
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Holo Transferrin
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Kawabata H. Transferrin and transferrin receptors update Free Radic Biol Med. 2019 Mar;133:46-54.
2: Zhang Z, Lu M, Chen C, Tong X, Li Y, Yang K, Lv H, Xu J, Qin L. Holo-lactoferrin: the link between ferroptosis and radiotherapy in triple-negative breast cancer Theranostics. 2021 Jan 1;11(7):3167-3182.
3: Tillib SV, Goryainova OS, Sachko AM, Ivanova TI. High-Affinity Single-Domain Antibodies for Analyzing Human Apo- and Holo-Transferrin Acta Naturae. 2022 Apr-Jun;14(2):98-102.
4: Booyjzsen C, Scarff CA, Moreton B, Portman I, Scrivens JH, Costantini G, Sadler PJ. Fibrillation of transferrin Biochim Biophys Acta. 2012 Mar;1820(3):427-36.
5: Baringer SL, Neely EB, Palsa K, Simpson IA, Connor JR. Regulation of brain iron uptake by apo- and holo_transferrin is dependent on sex and delivery protein Fluids Barriers CNS. 2022 Jun 10;19(1):49.
6: Sun Y, Wang X, Li J, Xue F, Tang F, Dai J. Extraintestinal pathogenic Escherichia coli utilizes the surface-expressed elongation factor Tu to bind and acquire iron from holo-transferrin Virulence. 2022 Dec;13(1):698-713.
7: Baringer SL, Palsa K, Simpson IA, Connor JR. Apo- and holo- transferrin differentially interact with ferroportin and hephaestin to regulate iron release at the blood-brain barrier bioRxiv. 2023 Jan 10:2023.01.10.522344.
8: Sun JL, Zhang NP, Xu RC, Zhang GC, Liu ZY, Abuduwaili W, Wang F, Yu XN, Shi X, Song GQ, Wu H, Liu TT, Shen XZ, Deng B, Weng SQ, Dong L, Zhu JM. Tumor cell-imposed iron restriction drives immunosuppressive polarization of tumor-associated macrophages J Transl Med. 2021 Aug 13;19(1):347.
9: Campos-Escamilla C, Siliqi D, Gonzalez-Ramirez LA, Lopez-Sanchez C, Gavira JA, Moreno A. X-ray Characterization of Conformational Changes of Human Apo- and Holo-Transferrin Int J Mol Sci. 2021 Dec 13;22(24):13392.
10: de Almeida SV, Cancino-Bernardi J, de Andrade JK, Felsner ML, Zucolotto V, Galli A. Cancer immunosensor based on apo and holo transferrin binding Mikrochim Acta. 2020 Jul 10;187(8):438.

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