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Fas Ligand (Human Recombinant)

$1,595.00

Catalog Number: B2010566 (10 ug)
Fas Ligand (Human Recombinant) is a highly pure recombinant human Fas ligand expressed in HEK293 cells. This product has been used as molecular in the study of various cellular systems. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2010566 Categories: ,

Description

Fas Ligand (Human Recombinant)
Catalog number: B2010566
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 ug
Molecular Weight or Concentration: na
Supplied as: Solution
Applications: molecular in the study of various cellular systems
Storage: -20C
Keywords: CD95L, CD178
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Rieux-Laucat F, Magérus-Chatinet A, Neven B. The Autoimmune
Lymphoproliferative Syndrome with Defective FAS or FAS-Ligand Functions. J Clin
Immunol. 2018 Jul;38(5):558-568.

2: Sato Y, Yoshino H, Tsuruga E, Kashiwakura I. Fas Ligand Enhances Apoptosis of
Human Lung Cancer Cells Cotreated with RIG-I-like Receptor Agonist and
Radiation. Curr Cancer Drug Targets. 2020;20(5):372-381.

3: Modiano JF, Bellgrau D. Fas ligand based immunotherapy: A potent and
effective neoadjuvant with checkpoint inhibitor properties, or a systemically
toxic promoter of tumor growth? Discov Med. 2016 Feb;21(114):109-16.

4: Guégan JP, Legembre P. Nonapoptotic functions of Fas/CD95 in the immune
response. FEBS J. 2018 Mar;285(5):809-827.

5: Glukhova XA, Trizna JA, Proussakova OV, Gogvadze VG, Beletsky IP.
Dephosphorylation of Fas_ligand and caveolin-1 is a prerequisite step in Fas-
ligand – caveolin-1 complex formation and cell death stimulation. Cell Signal.
2020 Jun;70:109590.

6: Owen-Schaub L, Chan H, Cusack JC, Roth J, Hill LL. Fas and Fas ligand
interactions in malignant disease. Int J Oncol. 2000 Jul;17(1):5-12.

7: Puppo F, Ghio M, Contini P, Mazzei C, Indiveri F. Fas, Fas_ligand,and
transfusion immunomodulation. Transfusion. 2001 Mar;41(3):416-8.

8: Wang T, Lian Y. The relationship between Fas and Fas_ligand gene polymorphism
and preeclampsia risk. Biosci Rep. 2019 Feb 15;39(2):BSR20181901.

9: O’Brien DI, Nally K, Kelly RG, O’Connor TM, Shanahan F, O’Connell J.
Targeting the Fas/Fas_ligand pathway in cancer. Expert Opin Ther Targets. 2005
Oct;9(5):1031-44.
10: Murata J, Abe R. Soluble Fas ligand: is it a critical mediator of toxic
epidermal necrolysis and Stevens-Johnson syndrome? J Invest Dermatol. 2007
Apr;127(4):744-5.

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