Factor XII Depleted Human Plasma


Catalog Number: B2012558 (5 mL)
Factor XII Depleted Human Plasma is a high quality human plasma that has been immuno-depleted of Factor XII. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2012558 Categories: , Tag:


Factor XII Depleted Human Plasma
Catalog number: B2012558
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mL
Molecular Weight or Concentration: N/A
Supplied as: Plasma
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: FXII Deficient plasma
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Caballero T. Treatment of Hereditary Angioedema J Investig Allergol Clin Immunol. 2021 Feb;31(1):1-16.
2: Fuhrer G, Gallimore MJ, Heller W, Hoffmeister HE. FXII Blut. 1990 Nov;61(5):258-66.
3: Mailer RK, Rangaswamy C, Konrath S, Emsley J, Renné T. An update on factor XII-driven vascular inflammation Biochim Biophys Acta Mol Cell Res. 2022 Jan;1869(1):119166.
4: Konrath S, Mailer RK, Beerens M, Englert H, Frye M, Kuta P, Preston RJS, Maas C, Butler LM, Roest M, de Laat B, Renné T. Intrinsic coagulation pathway-mediated thrombin generation in mouse whole blood Front Cardiovasc Med. 2022 Nov 28;9:1008410.
5: Wilmot HV, Hockley J, Rigsby P, Gray E. Establishment of the World Health Organization First International Standard for Factor XII, Plasma, Human Front Med (Lausanne). 2018 Feb 28;5:46.
6: Nickel KF, Long AT, Fuchs TA, Butler LM, Renné T. Factor XII as a Therapeutic Target in Thromboembolic and Inflammatory Diseases Arterioscler Thromb Vasc Biol. 2017 Jan;37(1):13-20.
7: Feugray G, Kasonga F, Chamouni P, Barbay V, Fresel M, Hélène Chretien M, Brunel S, Le Cam Duchez V, Billoir P. Factor XII deficiency evaluated by thrombin generation assay Clin Biochem. 2022 Feb;100:42-47.
8: Briseid K, Hoem NO, Johannesen S, Vangen AM, Westgaard T. Significance of IgG for the activity of factor XII measured in human plasma Scand J Clin Lab Invest. 1996 Dec;56(8):725-34.
9: Golas A, Yeh CH, Pitakjakpipop H, Siedlecki CA, Vogler EA. A comparison of blood factor XII autoactivation in buffer, protein cocktail, serum, and plasma solutions Biomaterials. 2013 Jan;34(3):607-20.
10: Gailani D, Broze GJ Jr. Factor XII-independent activation of factor XI in plasma: effects of sulfatides on tissue factor-induced coagulation Blood. 1993 Aug 1;82(3):813-9.

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