Dimethyl-Histone H3 (Lys27) Peptide Biotinylated

Description

Dimethyl-Histone H3 (Lys27) Peptide Biotinylated
Catalog number: B2012656
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: N/A
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Dimethyl-Histone H3 (Lys27) Peptide, biotin conjugate
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
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2: Amano Y, Kikuchi M, Sato S, Yokoyama S, Umehara T, Umezawa N, Higuchi T. Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1 Bioorg Med Chem. 2017 May 1;25(9):2617-2624.
3: Liu J, Xie Y, Guo J, Li X, Wang J, Jiang H, Peng Z, Wang J, Wang S, Li Q, Ye L, Zhong Y, Zhang Q, Liu X, Lonard DM, Wang J, O’Malley BW, Liu Z. Targeting NSD2-mediated SRC-3 liquid-liquid phase separation sensitizes bortezomib treatment in multiple myeloma Nat Commun. 2021 Feb 15;12(1):1022.
4: Ota Y, Kakizawa T, Itoh Y, Suzuki T. Design, Synthesis, and In Vitro Evaluation of Novel Histone H3 Peptide-Based LSD1 Inactivators Incorporating α,α-Disubstituted Amino Acids with γ-Turn-Inducing Structures Molecules. 2018 May 6;23(5):1099.
5: Liu H, Duan Y. Effects of posttranslational modifications on the structure and dynamics of histone H3 N-terminal Peptide Biophys J. 2008 Jun;94(12):4579-85.
6: Tu P, Li X, Ma B, Duan H, Zhang Y, Wu R, Ni Z, Jiang P, Wang H, Li M, Zhu J, Li M. Liver histone H3 methylation and acetylation may associate with type 2 diabetes development J Physiol Biochem. 2015 Mar;71(1):89-98.
7: Leon KE, Buj R, Lesko E, Dahl ES, Chen CW, Tangudu NK, Imamura-Kawasawa Y, Kossenkov AV, Hobbs RP, Aird KM. DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A J Cell Biol. 2021 Aug 2;220(8):e202008101.
8: Forneris F, Binda C, Dall’Aglio A, Fraaije MW, Battaglioli E, Mattevi A. A highly specific mechanism of histone H3-K4 recognition by histone demethylase LSD1 J Biol Chem. 2006 Nov 17;281(46):35289-95.
9: Meng CF, Zhu XJ, Peng G, Dai DQ. Promoter histone H3 lysine 9 di-methylation is associated with DNA methylation and aberrant expression of p16 in gastric cancer cells Oncol Rep. 2009 Nov;22(5):1221-7.
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