DAPK3 Active Human

Description

DAPK3 Active Human
Catalog number: B2013779
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 μg
Molecular Weight or Concentration: 79 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: DAPK3 Active Human
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Li GM, Li L, Li MQ, Chen X, Su Q, Deng ZJ, Liu HB, Li B, Zhang WH, Jia YX, Wang WJ, Ma JY, Zhang HL, Xie D, Zhu XF, He YL, Guan XY, Bi J. DAPK3 inhibits gastric cancer progression via activation of ULK1-dependent autophagy Cell Death Differ. 2021 Mar;28(3):952-967.
2: Takahashi M, Lio CJ, Campeau A, Steger M, Ay F, Mann M, Gonzalez DJ, Jain M, Sharma S. The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING-IFN-_ pathway Nat Immunol. 2021 Apr;22(4):485-496.
3: Li X, Liu J, Lu L, Huang T, Hou W, Wang F, Yu L, Wu F, Qi J, Chen X, Meng Z, Zhu M. Sirt7 associates with ELK1 to participate in hyperglycemia memory and diabetic nephropathy via modulation of DAPK3 expression and endothelial inflammation Transl Res. 2022 Sep;247:99-116.
4: Liu W, Zhang B, Zhang D, Guo F, Ye K, Zhu L, Jin X. The RBPJ/DAPK3/UBE3A signaling axis induces PBRM1 degradation to modulate the sensitivity of renal cell carcinoma to CDK4/6 inhibitors Cell Death Dis. 2022 Apr 2;13(4):295.
5: Kocher BA, White LS, Piwnica-Worms D. DAPK3 suppresses acini morphogenesis and is required for mouse development Mol Cancer Res. 2015 Feb;13(2):358-67.
6: Turner SR, Al-Ghabkari A, Carlson DA, Chappellaz M, Sutherland C, Haystead TAJ, Cole WC, MacDonald JA. Death-associated protein kinase 3 regulates the myogenic reactivity of cerebral arteries Exp Physiol. 2023 Apr 21.
7: Brognard J, Zhang YW, Puto LA, Hunter T. Cancer-associated loss-of-function mutations implicate DAPK3 as a tumor-suppressing kinase Cancer Res. 2011 Apr 15;71(8):3152-61.
8: Kake S, Usui T, Ohama T, Yamawaki H, Sato K. Death-associated protein kinase 3 controls the tumor progression of A549 cells through ERK MAPK/c-Myc signaling Oncol Rep. 2017 Feb;37(2):1100-1106.
9: Das TP, Suman S, Papu John AM, Pal D, Edwards A, Alatassi H, Ankem MK, Damodaran C. Activation of AKT negatively regulates the pro-apoptotic function of death-associated protein kinase 3 (DAPK3) in prostate cancer Cancer Lett. 2016 Jul 28;377(2):134-9.
10: Li KX, Du Q, Wang HP, Sun HJ. Death-associated protein kinase 3 deficiency alleviates vascular calcification via AMPK-mediated inhibition of endoplasmic reticulum stress Eur J Pharmacol. 2019 Jun 5;852:90-98.

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