D-3-Hydroxybutyrate dehydrogenase

Product Description

D-3-Hydroxybutyrate dehydrogenase (High Specific Activity)
Catalog number: B2010651
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 U
Molecular Weight or Concentration: na
Supplied as: Powder
Applications: enzyme that transforms D-3-Hydroxybutyrate into Acetoacetate
Storage: -20C
Keywords: 3-Hydroxybutyrate dehydrogenase, D-3-HBD
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Kanazawa H, Hoque MM, Tsunoda M, Suzuki K, Yamamoto T, Kawai G, Kondo J,
Takénaka A. Structural insights into the catalytic reaction trigger and
inhibition of D-3-hydroxybutyrate dehydrogenase. Acta Crystallogr F Struct Biol
Commun. 2016 Jul;72(Pt 7):507-15.

2: Ito K, Nakajima Y, Ichihara E, Ogawa K, Katayama N, Nakashima K, Yoshimoto T.
D-3-hydroxybutyrate dehydrogenase from Pseudomonas fragi: molecular cloning of
the enzyme gene and crystal structure of the enzyme. J Mol Biol. 2006 Jan
27;355(4):722-33.

3: Preuveneers MJ, Peacock D, Crook EM, Clark JB, Brocklehurst K.
D-3-hydroxybutyrate dehydrogenase from Rhodopseudomonas spheroides. Kinetics of
radioisotope redistribution at chemical equilibrium catalysed by the enzyme in
solutions. Biochem J. 1973 May;133(1):159-64.

4: Koyappayil A, Chavan SG, Mohammadniaei M, Go A, Hwang SY, Lee MH.
β-Hydroxybutyrate dehydrogenase decorated MXene nanosheets for the amperometric
determination of β-hydroxybutyrate. Mikrochim Acta. 2020 Apr 20;187(5):277.

5: Machado TFG, Purg M, Åqvist J, da Silva RG. Transition States for
Psychrophilic and Mesophilic (R)-3-Hydroxybutyrate Dehydrogenase-
Catalyzed Hydride Transfer at Sub-zero Temperatures. Biochemistry. 2021 Jul
13;60(27):2186-2194.

6: Hoque MM, Shimizu S, Juan EC, Sato Y, Hossain MT, Yamamoto T, Imamura S,
Suzuki K, Amano H, Sekiguchi T, Tsunoda M, Takénaka A. Structure of
D-3-hydroxybutyrate dehydrogenase prepared in the presence of the substrate
D-3-hydroxybutyrate and NAD+. Acta Crystallogr Sect F Struct Biol Cryst Commun.
2009 Apr 1;65(Pt 4):331-5.

7: ROSALKI SB. alpha-Hydroxybutyrate-dehydrogenase. Lancet. 1963 Mar
9;1(7280):544-5.

8: Nakashima K, Ito K, Nakajima Y, Yamazawa R, Miyakawa S, Yoshimoto T. Closed
complex of the D-3-hydroxybutyrate dehydrogenase induced by an enantiomeric
competitive inhibitor. J Biochem. 2009 Apr;145(4):467-79.

9: Taxon ES, Halbers LP, Parsons SM. Kinetics aspects of Gamma-hydroxybutyrate
dehydrogenase. Biochim Biophys Acta Proteins Proteom. 2020 May;1868(5):140376.
10: Liu Z, Velpula KK, Devireddy L. 3-Hydroxybutyrate dehydrogenase-2 and
ferritin-H synergistically regulate intracellular iron. FEBS J. 2014
May;281(10):2410-21.

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