Collagen Type II, Monoclonal Antibody

Product Description

Collagen Type II, Monoclonal Antibody
Catalog number: B2026941
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: NA
Supplied as: Solution
Storage: −20°C
Keywords: Collagen Type II, Human Collagen, Collagen, Collagen Hydrolysate, Collagen Peptides, Hydrolyzed Collagen, Native Collagen, Type 2 Collagen, COL2A1, SEDC

References:
“1. Lindh, I., Snir, O., Lonnblom, E., Schwenk, J. M., Klareskog, L., and Holmdahl, R. Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis. J Exp Med. 2009 Feb 16;206(2):449-62.
2. Burkhardt, H., Sehnert, B., Bockermann, R., Engstrom, A., Kalden, J. R., and Holmdahl, R. Humoral immune response to citrullinated collagen type II in arthritis. Arthritis Rheum. 2005;52(11):3393-406.
3. Nandakumar, K. S., and Holmdahl, R. Antibody-induced arthritis: genes, cells and mechanisms. Biochem Soc Trans. 2007;35(Pt 4):670-2.
4. Croxford, A. M., Nandakumar, K. S., and Holmdahl, R. The role of effector cells in the end-stage effector phase of arthritis pathogenesis. Arthritis Res Ther. 2010;12(5):R175.
5. Manivel, V. A., Sohrabian, A., Rethi, B., Erlandsson, M. C., Bokarewa, M. I., and Holmdahl, R. Anti-collagen type II antibodies are associated with early joint destruction in rheumatoid arthritis. Arthritis Res Ther. 2015;17:229.
6. Mullazehi, M., Wick, M. C., Klareskog, L., van Vollenhoven, R., and Ronnelid, J. Anti-native type II collagen antibodies are associated with early erosions in rheumatoid arthritis. Ann Rheum Dis. 2007;66(8):1037-41.
7. Schulte, S., Unger, C., Mo, J. A., Wendler, O., Bauer, E., Frischholz, S., and Burkhardt, H. Arthritis-inducing antibodies specific for collagen type II are not only cytotoxic but also directly inhibit the assembly of collagen fibrils. Arthritis Rheum. 1998;41(2):313-21.
8. Uysal, H., Bockermann, R., Nandakumar, K. S., Sehnert, B., Bajtner, E., Engstrom, A., and Holmdahl, R. Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis. J Exp Med. 2009;206(2):449-62.
9. Nandakumar, K. S., Svensson, L., and Holmdahl, R. Collagen type II-specific monoclonal antibodies induce arthritis in mice. Arthritis Res Ther. 2003;5(4):R163-9.
10. Bajtner, E., Nandakumar, K. S., Engstrom, A., and Holmdahl, R. Chronic development of collagen-induced arthritis is associated with a restricted antibody response to type II collagen. Clin Exp Immunol. 2002;128(2):235-42.”
Collagen Type II, Monoclonal Antibody (Clone M2139)

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