Chenodeoxycholic Acid (Highly Pure)


Catalog Number: B2010637 (25 mg)
Chenodeoxycholic Acid (Highly Pure) is a highly pure bile acid derived from cholesterol. This product has been used as molecular tool in the sutdy of various metabolic systems. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2010637 Categories: ,


Chenodeoxycholic Acid (Highly Pure)
Catalog number: B2010637
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 25 mg
Molecular Weight or Concentration: 392.57 g/mol
Supplied as: Powder
Applications: molecular tool in the sutdy of various metabolic systems
Storage: RT
Keywords: Chenodiol, 5β-Cholanic acid-3α,7α-diol, 3α,7α-Dihydroxy-5β-cholanic acid
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Chenodeoxycholic acid. Lancet. 1978 Apr 15;1(8068):805.

2: Shah RA, Kowdley KV. Obeticholic acid for the treatment of nonalcoholic
steatohepatitis. Expert Rev Gastroenterol Hepatol. 2020 May;14(5):311-321.

3: Chenodeoxycholic acid in the dissolution of gallstones. Nutr Rev. 1976

4: Iser JH, Sali A. Chenodeoxycholic_acid: a review of its pharmacological
properties and therapeutic use. Drugs. 1981 Feb;21(2):90-119.

5: Hofmann AF. Desaturation of bile and cholesterol gallstone dissolution with
chenodeoxycholic_acid. Am J Clin Nutr. 1977 Jun;30(6):993-1000.

6: Tint GS, Salen G, Shefer S. Effect of ursodeoxycholic acid and
chenodeoxycholic acid on cholesterol and bile acid metabolism. Gastroenterology.
1986 Oct;91(4):1007-18.

7: Fiorucci S, Di Giorgio C, Distrutti E. Obeticholic Acid: An Update of Its
Pharmacological Activities in Liver Disorders. Handb Exp Pharmacol.

8: Wang H, He Q, Wang G, Xu X, Hao H. FXR modulators for enterohepatic and
metabolic diseases. Expert Opin Ther Pat. 2018 Nov;28(11):765-782.

9: Ratziu V, Sanyal AJ, Loomba R, Rinella M, Harrison S, Anstee QM, Goodman Z,
Bedossa P, MacConell L, Shringarpure R, Shah A, Younossi Z. REGENERATE: Design
of a pivotal, randomised, phase 3 study evaluating the safety and efficacy of
obeticholic acid in patients with fibrosis due to nonalcoholic steatohepatitis.
Contemp Clin Trials. 2019 Sep;84:105803.
10: Corazziari E, Pozzessere C, Dani S, Piccinni-Leopardi M, Anzini F,
Alessandrini A. Chenodeoxycholic acid and diarrhoea. Lancet. 1978 Jul

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