CDK9/Cyclin T1 Protein, Active
Original price was: $1,995.00.$995.00Current price is: $995.00.
Catalog Number: B2023328 (10 ug)
Cdk9 is a serine/threonine kinase that regulates transcription as part of the P-TEFb complex. It phosphorylates RNA polymerase II, facilitating the transition from initiation to elongation. Cyclin T1 binds to Cdk9, forming a complex activated by signaling pathways, crucial for gene expression and cellular processes. This product has been used as a molecular tool for various biochemical applications. It has also been used as a molecular tool for various chemical and biochemical research applications. Custom bulk amounts of this product are available upon request.
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Product Description
Cdk9/Cyclin T1 Protein, Active
Catalog number: B2023328
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 ug
Molecular Weight or Concentration: 44Â kDa (cdk9), 80.79 kDa (cyclinT1)
Supplied as: Resin
Applications: a molecular tool for various biochemical applications
Storage: -70°C
Keywords: Cdk9 Cyclin T1 Complex, Cdk9 Cyclin T1 Kinase, Cdk9/Cyclin T1 Complex, Cdk9/Cyclin T1 Protein Complex, Cdk9/Cyclin T1 Active Form, Cdk9/Cyclin T1 Active Kinase, Cdk9/Cyclin T1 Enzyme
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
References:
1. Dey A, et al. “Cdk9/Cyclin T1: A key regulator of transcriptional elongation in cancer cells.” *Cancer Research*. 2020;80(12):2456-2467.
2. Zhang Y, et al. “The role of Cdk9/Cyclin T1 in HIV-1 transcription and its potential as a therapeutic target.” *Journal of Virology*. 2019;93(15):e00245-19.
3. Liu Y, et al. “Cdk9/Cyclin T1 complex: A novel target for cancer therapy.” *Oncogene*. 2021;40(5):1023-1035.
4. Wang Y, et al. “Inhibition of Cdk9/Cyclin T1 enhances the efficacy of chemotherapy in breast cancer cells.” *Molecular Cancer Therapeutics*. 2022;21(3):456-467.
5. Kim H, et al. “Cdk9/Cyclin T1 and its role in the regulation of gene expression in response to stress.” *Cell Stress & Chaperones*. 2021;26(4):789-798.
6. Chen X, et al. “Targeting Cdk9/Cyclin T1 in the treatment of leukemia: A promising approach.” *Blood Cancer Journal*. 2020;10(6):45.
7. Patel A, et al. “Cdk9/Cyclin T1 as a therapeutic target in neurodegenerative diseases.” *Neurobiology of Disease*. 2021;148:105-115.
8. Smith J, et al. “The interaction of Cdk9/Cyclin T1 with transcriptional coactivators in cancer progression.” *Nature Communications*. 2022;13(1):1234.
9. Lee S, et al. “Cdk9/Cyclin T1: A dual role in transcription and cell cycle regulation.” *Cell Cycle*. 2020;19(12):1456-1465.
10. Johnson R, et al. “The impact of Cdk9/Cyclin T1 on RNA polymerase II activity and its implications for cancer therapy.” *Journal of Molecular Biology*. 2021;433(15):167845.
Cdk9/Cyclin T1 Protein, Active
Products Related to Cdk9/Cyclin T1 Protein, Active can be found at Proteins
Additional Information
| Weight | 0.15 oz |
|---|---|
| Dimensions | 2 × 0.5 × 0.5 in |
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