Catechol O-Methyl Transferase

Product Description

Catechol O-Methyl Transferase
Catalog number: B2013248
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 kU
Molecular Weight or Concentration: 4000 U/mg
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20C
Keywords: COMT
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Sagud M, Mück-Seler D, Mihaljević-Peles A, Vuksan-Cusa B, Zivković M, Jakovljević M, Pivac N. Catechol-O-methyl transferase and schizophrenia Psychiatr Danub. 2010 Jun;22(2):270-4.
2: Sambataro F, Pennuto M, Christian Wolf R. Catechol_o-methyl transferase modulates cognition in late life: evidence and implications for cognitive enhancement CNS Neurol Disord Drug Targets. 2012 May;11(3):195-208.
3: Guldberg HC, Marsden CA. Catechol-O-methyl transferase: pharmacological aspects and physiological role Pharmacol Rev. 1975 Jun;27(2):135-206.
4: Nishiwaki H, Ito M, Ishida T, Hamaguchi T, Maeda T, Kashihara K, Tsuboi Y, Ueyama J, Shimamura T, Mori H, Kurokawa K, Katsuno M, Hirayama M, Ohno K. Meta-Analysis of Gut Dysbiosis in Parkinson’s Disease Mov Disord. 2020 Sep;35(9):1626-1635.
5: Phoswa WN. Dopamine in the Pathophysiology of Preeclampsia and Gestational Hypertension: Monoamine Oxidase (MAO) and Catechol-O-methyl Transferase (COMT) as Possible Mechanisms Oxid Med Cell Longev. 2019 Nov 28;2019:3546294.
6: Craddock N, Owen MJ, O’Donovan MC. The catechol-O_methyl transferase (COMT) gene as a candidate for psychiatric phenotypes: evidence and lessons Mol Psychiatry. 2006 May;11(5):446-58.
7: Männistö PT, Ulmanen I, Lundström K, Taskinen J, Tenhunen J, Tilgmann C, Kaakkola S. Characteristics of catechol O_methyl-transferase (COMT) and properties of selective COMT inhibitors Prog Drug Res. 1992;39:291-350.
8: Janacova L, Stenckova M, Lapcik P, Hrachovinova S, Bouchalova P, Potesil D, Hrstka R, Müller P, Bouchal P. Catechol-O_methyl transferase suppresses cell invasion and interplays with MET signaling in estrogen dependent breast cancer Sci Rep. 2023 Jan 23;13(1):1285.
9: Parrales-Macias V, Harfouche A, Ferrié L, Haïk S, Michel PP, Raisman-Vozari R, Figadère B, Bizat N, Maciuk A. Effects of a New Natural Catechol_O-methyl Transferase Inhibitor on Two In Vivo Models of Parkinson’s Disease ACS Chem Neurosci. 2022 Dec 7;13(23):3303-3313.
10: Tolba MF, Omar HA, Hersi F, Nunes ACF, Noreddin AM. The impact of Catechol-O-methyl transferase knockdown on the cell proliferation of hormone-responsive cancers Mol Cell Endocrinol. 2019 May 15;488:79-88.

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