Carbonic Anhydrase 2 (CA2)

Product Description

Carbonic Anhydrase 2 (CA2)
Catalog number: B2014948
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 ug
Molecular Weight or Concentration: 27 kDa
Supplied as: Liquid
Applications: molecular tool for various biochemical applications
Storage: -80°C
Keywords: Carbonate Dehydratase II, Carbonic Anhydrase C, CAC, Carbonic Anhydrase II, CA-II.
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Whyte MP. Carbonic anhydrase II deficiency Bone. 2023 Apr;169:116684.
2: Shaik NA, Bokhari HA, Masoodi TA, Shetty PJ, Ajabnoor GMA, Elango R, Banaganapalli B. Molecular modelling and dynamics of CA2 missense mutations causative to carbonic anhydrase 2 deficiency syndrome J Biomol Struct Dyn. 2020 Sep;38(14):4067-4080.
3: Zhang C, Wang H, Chen Z, Zhuang L, Xu L, Ning Z, Zhu Z, Wang P, Meng Z. Carbonic anhydrase 2 inhibits epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma Carcinogenesis. 2018 Apr 5;39(4):562-570.
4: Zhao K, Schäfer A, Zhang Z, Elsässer K, Culmsee C, Zhong L, Pagenstecher A, Nimsky C, Bartsch JW. Inhibition of Carbonic Anhydrase 2 Overcomes Temozolomide Resistance in Glioblastoma Cells Int J Mol Sci. 2021 Dec 23;23(1):157.
5: Jiang C, Shi J, Liao L, Zhang L, Liu J, Wang Y, Lao Y, Zhang J. 5-[2-(N-(Substituted phenyl)acetamide)]amino-1,3,4-thiadiazole-2-sulfonamides as Selective Carbonic Anhydrase II Inhibitors with Neuroprotective Effects ChemMedChem. 2020 Apr 20;15(8):705-715.
6: Tachibana H, Gi M, Kato M, Yamano S, Fujioka M, Kakehashi A, Hirayama Y, Koyama Y, Tamada S, Nakatani T, Wanibuchi H. Carbonic anhydrase 2 is a novel invasion-associated factor in urinary bladder cancers Cancer Sci. 2017 Mar;108(3):331-337.
7: Du X, Cui Z, Ning Z, Deng X, Amevor FK, Shu G, Wang X, Zhang Z, Tian Y, Zhu Q, Wang Y, Li D, Zhang Y, Zhao X. Circadian miR-218-5p targets gene CA2 to regulate uterine carbonic anhydrase activity during egg shell calcification Poult Sci. 2022 Nov;101(11):102158.
8: Ip YK, Koh CZY, Hiong KC, Choo CYL, Boo MV, Wong WP, Neo ML, Chew SF. Carbonic anhydrase 2-like in the giant clam, Tridacna squamosa: characterization, localization, response to light, and possible role in the transport of inorganic carbon from the host to its symbionts Physiol Rep. 2017 Dec;5(23):e13494.
9: Strowitzki MJ, Nelson R, Garcia MP, Tuffs C, Bleul MB, Fitzsimons S, Navas J, Uzieliene I, Ritter AS, Phelan D, Kierans SJ, Blanco A, Bernotiene E, Belton O, Schneider M, Cummins EP, Taylor CT. Carbon Dioxide Sensing by Immune Cells Occurs through Carbonic Anhydrase 2-Dependent Changes in Intracellular pH J Immunol. 2022 May 15;208(10):2363-2375.
10: Su H, Hu K, Liu Z, Chen K, Xu J. Carbonic anhydrase 2 and 3 as risk biomarkers for dilated cardiomyopathy associated heart failure Ann Palliat Med. 2021 Dec;10(12):12554-12565.

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