Calpain Substrate III Fluorogenic

Product Description

Calpain Substrate III Fluorogenic
Catalog number: B2014006
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 1675.9 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: Calpain Substrate III, Fluorogenic
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Goll DE, Thompson VF, Li H, Wei W, Cong J. The calpain system Physiol Rev. 2003 Jul;83(3):731-801.
2: Nakazawa T, Shimura M, Mourin R, Kondo M, Yokokura S, Saido TC, Nishida K, Endo S. Calpain-mediated degradation of G-substrate plays a critical role in retinal excitotoxicity for amacrine cells J Neurosci Res. 2009 May 1;87(6):1412-23.
3: Liu Y, Che X, Zhang H, Fu X, Yao Y, Luo J, Yang Y, Cai R, Yu X, Yang J, Zhou MS. CAPN1 (Calpain1)-Mediated Impairment of Autophagic Flux Contributes to Cerebral Ischemia-Induced Neuronal Damage Stroke. 2021 May;52(5):1809-1821.
4: Bordone L, Campbell C. DNA ligase III is degraded by calpain during cell death induced by DNA-damaging agents J Biol Chem. 2002 Jul 19;277(29):26673-80.
5: Siman R, Baudry M, Lynch G. Brain fodrin: substrate for calpain I, an endogenous calcium-activated protease Proc Natl Acad Sci U S A. 1984 Jun;81(11):3572-6.
6: Belcastro AN, Shewchuk LD, Raj DA. Exercise-induced muscle injury: a calpain hypothesis Mol Cell Biochem. 1998 Feb;179(1-2):135-45.
7: Ali MA, Stepanko A, Fan X, Holt A, Schulz R. Calpain inhibitors exhibit matrix metalloproteinase-2 inhibitory activity Biochem Biophys Res Commun. 2012 Jun 22;423(1):1-5.
8: Garcia M, Bondada V, Geddes JW. Mitochondrial localization of mu-calpain Biochem Biophys Res Commun. 2005 Dec 16;338(2):1241-7.
9: Kurbatskaya K, Phillips EC, Croft CL, Dentoni G, Hughes MM, Wade MA, Al-Sarraj S, Troakes C, O’Neill MJ, Perez-Nievas BG, Hanger DP, Noble W. Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer’s disease brain Acta Neuropathol Commun. 2016 Mar 31;4:34.
10: Fernndez-Montalvn A, Assfalg-Machleidt I, Pfeiler D, Fritz H, Jochum M, Machleidt W. Electrostatic interactions of domain III stabilize the inactive conformation of mu-calpain Biochem J. 2004 Sep 1;382(Pt 2):607-17.

Products Related to Calpain Substrate III Fluorogenic can be found at Substrates