Beta Lactamase Protein

Product Description

Beta Lactamase Protein
Catalog number: B2011603
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 1 mg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: ampC protein, ampA protein, D-alanine carboxypeptidase protein, Cephalosporinase protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Yadav TC, Agarwal V, Srivastava AK, Raghuwanshi N, Varadwaj P, Prasad R, Pruthi V. Insight into Structure-Function Relationships of β-Lactamase and BLIPs Interface Plasticity using Protein-Protein Interactions Curr Pharm Des. 2019;25(31):3378-3389.
2: Bush K. Past and Present Perspectives on β-Lactamases Antimicrob Agents Chemother. 2018 Sep 24;62(10):e01076-18.
3: Eiamphungporn W, Schaduangrat N, Malik AA, Nantasenamat C. Tackling the Antibiotic Resistance Caused by Class A β-Lactamases through the Use of β-Lactamase Inhibitory Protein Int J Mol Sci. 2018 Jul 30;19(8):2222.
4: Dever LA, Dermody TS. Mechanisms of bacterial resistance to antibiotics Arch Intern Med. 1991 May;151(5):886-95.
5: Toussaint KA, Gallagher JC. β-lactam/β-lactamase inhibitor combinations: from then to now Ann Pharmacother. 2015 Jan;49(1):86-98.
6: Salahuddin P, Kumar A, Khan AU. Structure, Function of Serine and Metallo-β-lactamases and their Inhibitors Curr Protein Pept Sci. 2018;19(2):130-144.
7: Huang L, So PK, Chen YW, Leung YC, Yao ZP. Interdomain flexibility and interfacial integrity of β-lactamase inhibitory protein (BLIP) modulate its binding to class A β-lactamases J Biol Chem. 2021 Aug;297(2):100980.
8: Docquier JD, Mangani S. An update on β-lactamase inhibitor discovery and development Drug Resist Updat. 2018 Jan;36:13-29.
9: Tadayyon M, Zhang Y, Gnaneshan S, Hunt L, Mehraein-Ghomi F, Broome-Smith JK. beta-Lactamase fusion analysis of membrane protein assembly Biochem Soc Trans. 1992 Aug;20(3):598-601.
10: Knoverek CR, Mallimadugula UL, Singh S, Rennella E, Frederick TE, Yuwen T, Raavicharla S, Kay LE, Bowman GR. Opening of a cryptic pocket in β-lactamase increases penicillinase activity Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2106473118.

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