Bacterial Sortase Substrate III

Product Description

Bacterial Sortase Substrate III
Catalog number: B2011396
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 928 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: Bacterial Sortase Substrate III, Abz/DNP
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Scott CJ, McDowell A, Martin SL, Lynas JF, Vandenbroeck K, Walker B. Irreversible inhibition of the bacterial cysteine protease-transpeptidase sortase (SrtA) by substrate-derived affinity labels Biochem J. 2002 Sep 15;366(Pt 3):953-8.
2: Das S, Pawale VS, Dadireddy V, Singh AK, Ramakumar S, Roy RP. Structure and specificity of a new class of Ca(2+)-independent housekeeping sortase from Streptomyces avermitilis provide insights into its non-canonical substrate preference J Biol Chem. 2017 Apr 28;292(17):7244-7257.
3: Kruger RG, Otvos B, Frankel BA, Bentley M, Dostal P, McCafferty DG. Analysis of the substrate specificity of the Staphylococcus aureus sortase transpeptidase SrtA Biochemistry. 2004 Feb 17;43(6):1541-51.
4: Suree N, Liew CK, Villareal VA, Thieu W, Fadeev EA, Clemens JJ, Jung ME, Clubb RT. The structure of the Staphylococcus aureus sortase-substrate complex reveals how the universally conserved LPXTG sorting signal is recognized J Biol Chem. 2009 Sep 4;284(36):24465-77.
5: Perry AM, Ton-That H, Mazmanian SK, Schneewind O. Anchoring of surface proteins to the cell wall of Staphylococcus aureus. III. Lipid II is an in vivo peptidoglycan substrate for sortase-catalyzed surface protein anchoring J Biol Chem. 2002 May 3;277(18):16241-8.
6: Weiss JP. Molecular determinants of bacterial sensitivity and resistance to mammalian Group IIA phospholipase A2 Biochim Biophys Acta. 2015 Nov;1848(11 Pt B):3072-7.
7: Silvius JR, Leventis R. A Novel “Prebinding” Strategy Dramatically Enhances Sortase-Mediated Coupling of Proteins to Liposomes Bioconjug Chem. 2017 Apr 19;28(4):1271-1282.
8: Khare B, Fu ZQ, Huang IH, Ton-That H, Narayana SV. The crystal structure analysis of group B Streptococcus sortase C1: a model for the “lid” movement upon substrate binding J Mol Biol. 2011 Dec 9;414(4):563-77.
9: Marraffini LA, Schneewind O. Anchor structure of staphylococcal surface proteins. V. Anchor structure of the sortase B substrate IsdC J Biol Chem. 2005 Apr 22;280(16):16263-71.
10: Bentley ML, Lamb EC, McCafferty DG. Mutagenesis studies of substrate recognition and catalysis in the sortase A transpeptidase from Staphylococcus aureus J Biol Chem. 2008 May 23;283(21):14762-71.

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