Anti-Human IgG Antibody F(ab’)2 Biotinylated


Catalog Number: B2010892 (1 mg)
Anti-Human IgG Antibody F(ab’)2 Biotinylated is a highly pure biotin-labelled affinity purified polyclonal antibody, F(ab)2 fragment, to human IgG. This product has been used as molecular tool for various biochemical studies. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Anti-Human IgG Antibody F(ab’)2 Biotinylated
Catalog number: B2010892
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: na
Supplied as: Lyophilized powder
Applications: molecular tool for various biochemical studies
Storage: -20°C
Keywords: Biotinylated Anti-Human IgG Antibody F(ab’)2 Fragment
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Valedkarimi Z, Nasiri H, Aghebati-Maleki L, Abdolalizadeh J, Esparvarinha M, Majidi J. Production and characterization of anti-human IgG F(ab’)2 antibody fragment Hum Antibodies. 2018;26(4):171-176.
2: Leli C, Callegari T, Cassinari M, Rocchetti A. Kinetics of Anti-SARS-CoV-2 IgG among healthcare workers in a General Hospital New Microbiol. 2021 Apr;44(2):84-88. Epub 2021 May 21.
3: Harritshøj LH, Gybel-Brask M, Afzal S, Kamstrup PR, Jørgensen CS, Thomsen MK, Hilsted L, Friis-Hansen L, Szecsi PB, Pedersen L, Nielsen L, Hansen CB, Garred P, Korsholm TL, Mikkelsen S, Nielsen KO, Møller BK, Hansen AT, Iversen KK, Nielsen PB, Hasselbalch RB, Fogh K, Norsk JB, Kristensen JH, Schønning K, Kirkby NS, Nielsen ACY, Landsy LH, Loftager M, Holm DK, Nilsson AC, Sækmose SG, Grum-Schwensen B, Aagaard B, Jensen TG, Nielsen DM, Ullum H, Dessau RB. Comparison of 16 Serological SARS-CoV-2 Immunoassays in 16 Clinical Laboratories J Clin Microbiol. 2021 Apr 20;59(5):e02596-20.
4: Sherina N, Piralla A, Du L, Wan H, Kumagai-Braesch M, Andréll J, Braesch-Andersen S, Cassaniti I, Percivalle E, Sarasini A, Bergami F, Di Martino R, Colaneri M, Vecchia M, Sambo M, Zuccaro V, Bruno R, Sachs M, Oggionni T, Meloni F, Abolhassani H, Bertoglio F, Schubert M, Byrne-Steele M, Han J, Hust M, Xue Y, Hammarström L, Baldanti F, Marcotte H, Pan-Hammarström Q. Persistence of SARS-CoV-2-specific B and T cell responses in convalescent COVID-19 patients 6-8 months after the infection Med (N Y). 2021 Mar 12;2(3):281-295.e4.
5: Hunt Gerardo S, Persselin JE, Stevens RH. Human IgG anti-F(ab’)2 antibodies possess rheumatoid factor activity Clin Exp Immunol. 1990 Aug;81(2):293-300.
6: Ota T, Ota SI, Uchino A, Nagano S. IgG anti-hinge antibodies against IgG4 F(ab’)(2) fragments generated using pepsin are useful diagnostic markers for rheumatoid arthritis: implications of the possible roles of metalloproteinases and IgG subclasses in generating immunogenic hinge epitopes Arthritis Res Ther. 2020 Jun 26;22(1):161.
7: Welschof M, Terness P, Kipriyanov SM, Stanescu D, Breitling F, Dörsam H, Dübel S, Little M, Opelz G. The antigen-binding domain of a human IgG-anti-F(ab’)2 autoantibody Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1902-7.
8: Terness P, Kohl I, Hübener G, Battistutta R, Moroder L, Welschof M, Dufter C, Finger M, Hain C, Jung M, et al. The natural human IgG anti-F(ab’)2 antibody recognizes a conformational IgG1 hinge epitope J Immunol. 1995 Jun 15;154(12):6446-52.
9: Rubin RL, Carr RI. Anti-DNA activity of IgG F(ab’)2 from normal human serum J Immunol. 1979 Apr;122(4):1604-7.
10: Matsuura T, Imamura A, Ota T. [IgM Antibody against IgG Antibody Binding to Antigen, So-Called Anti-Antibody, Reacts Mainly with F (ab’)₂ Fragment Possessing Antibody Activity] Rinsho Byori. 2017 Jan;65(1):13-18.

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