Anti Human IgE Antibody (Epsilon Chain Specific) Conjugated to AP

Description

Anti Human IgE Antibody (Epsilon Chain Specific) Conjugated to AP
Catalog number: B2010787
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: na
Supplied as: Lyophilized
Applications: multipurpose antibody for various assay formats, including ELISA
Storage: -20C
Keywords: anti-IgE AP, Epsilon specific anti-IgE AP, anti-IgE Epsilon AP, anti-IgE Epsilon Alkaline Phosphatase
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: D’Amato G, Oldani V, Donner CF. Anti-IgE monoclonal antibody: a new approach to the treatment of allergic respiratory diseases Monaldi Arch Chest Dis. 2003 Jan-Mar;59(1):25-9.
2: Liu P, Pan Z, Gu C, Cao X, Liu X, Zhang J, Xiao Z, Wang X, Guo H, Ju D, Deng SJ. An Omalizumab Biobetter Antibody With Improved Stability and Efficacy for the Treatment of Allergic Diseases Front Immunol. 2020 Nov 27;11:596908.
3: Jabs F, Plum M, Laursen NS, Jensen RK, Mølgaard B, Miehe M, Mandolesi M, Rauber MM, Pfützner W, Jakob T, Möbs C, Andersen GR, Spillner E. Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction Nat Commun. 2018 Jan 2;9(1):7.
4: Deniz YM, Gupta N. Safety and tolerability of omalizumab (Xolair), a recombinant humanized monoclonal anti-IgE antibody Clin Rev Allergy Immunol. 2005 Aug;29(1):31-48.
5: Johansson SG, Oman H, Nopp A, Pettersson S. The importance of IgE antibody levels in anti-IgE treatment Allergy. 2006 Oct;61(10):1216-9.
6: Qian W, Zhang X, Li B, Zhang D, Tong Q, Chen L, Zheng L, Kou G, Wang H, Hou S, Guo Y. Development and characterization of a novel anti-IgE monoclonal antibody Biochem Biophys Res Commun. 2010 May 14;395(4):547-52.
7: Fried AJ, Oettgen HC. Anti-IgE in the treatment of allergic disorders in pediatrics Curr Opin Pediatr. 2010 Dec;22(6):758-64.
8: Chu SY, Horton HM, Pong E, Leung IW, Chen H, Nguyen DH, Bautista C, Muchhal US, Bernett MJ, Moore GL, Szymkowski DE, Desjarlais JR. Reduction of total IgE by targeted coengagement of IgE B-cell receptor and FcγRIIb with Fc-engineered antibody J Allergy Clin Immunol. 2012 Apr;129(4):1102-15.
9: Kopp MV. Omalizumab: Anti-IgE therapy in allergy Curr Allergy Asthma Rep. 2011 Apr;11(2):101-6.
10: Pelst MP, Maina E, Vandenabeele S, Hesta M, Cox E. Detection of allergen-specific antibody-secreting cells in dogs by ELISPOT Vet Immunol Immunopathol. 2020 Oct;228:110101.

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