Angiopoietin-like Protein 8


Catalog Number: B2012505 (10 ug)
Angiopoietin-like Protein 8 is a high quality recombinant angiopoietin-like protein 8. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Angiopoietin-like Protein 8
Catalog number: B2012505
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 ug
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: Angptl8
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Zhao Z, Deng X, Jia J, Zhao L, Wang C, Cai Z, Guo C, Yang L, Wang D, Ma S, Deng J, Li H, Zhou L, Tu Z, Yuan G. Angiopoietin-like protein 8 (betatrophin) inhibits hepatic gluconeogenesis through PI3K/Akt signaling pathway in diabetic mice Metabolism. 2022 Jan;126:154921.
2: Guo C, Zhao Z, Deng X, Chen Z, Tu Z, Yuan G. Regulation of angiopoietin_like protein 8 expression under different nutritional and metabolic status Endocr J. 2019 Dec 25;66(12):1039-1046.
3: Liu YZ, Zhang C, Jiang JF, Cheng ZB, Zhou ZY, Tang MY, Sun JX, Huang L. Angiopoietin-like proteins in atherosclerosis Clin Chim Acta. 2021 Oct;521:19-24.
4: Wang S, Hong X, Tu Z, Yuan G. Angiopoietin-like protein 8: An attractive biomarker for the evaluation of subjects with insulin resistance and related disorders Diabetes Res Clin Pract. 2017 Nov;133:168-177.
5: Wang D, Feng D, Wang Y, Dong P, Wang Y, Zhong L, Li B, Fu J, Xiao X, Speakman JR, Li M, Gao S. Angiopoietin-Like Protein 8/Leptin Crosstalk Influences Cardiac Mass in Youths With Cardiometabolic Risk: The BCAMS Study Front Endocrinol (Lausanne). 2022 Jan 25;12:788549.
6: Chen YQ, Pottanat TG, Siegel RW, Ehsani M, Qian YW, Roell WC, Konrad RJ. Angiopoietin_like protein 4(E40K) and ANGPTL4/8 complex have reduced, temperature-dependent LPL-inhibitory activity compared to ANGPTL4 Biochem Biophys Res Commun. 2021 Jan 1;534:498-503.
7: Huang W, Lin Y, Xiang H, Zhu J, Wang Y. Angiopoietin-like protein 8, molecular cloning and regulating lipid accumulation in goat intramuscular preadipocytes Anim Biotechnol. 2022 Oct;33(5):876-883.
8: Jiao X, Yang Y, Li L, Yu H, Yang Y, Li J, Du Y, Zhang J, Hu C, Qin Y. Angiopoietin_like protein 8 accelerates atherosclerosis in ApoE(-/)(-) mice Atherosclerosis. 2020 Aug;307:63-71.
9: Chen YQ, Pottanat TG, Siegel RW, Ehsani M, Qian YW, Zhen EY, Regmi A, Roell WC, Guo H, Luo MJ, Gimeno RE, Van’t Hooft F, Konrad RJ. Angiopoietin_like protein 8 differentially regulates ANGPTL3 and ANGPTL4 during postprandial partitioning of fatty acids J Lipid Res. 2020 Aug;61(8):1203-1220.
10: Chen YQ, Pottanat TG, Siegel RW, Ehsani M, Qian YW, Konrad RJ. Angiopoietin-like protein 4 (ANGPTL4) is an inhibitor of endothelial lipase (EL) while the ANGPTL4/8 complex has reduced EL-inhibitory activity Heliyon. 2021 Aug 30;7(9):e07898.

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