6-deoxy-6-[(5/6)-fluoresceinylthioureido]-BCD

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6-deoxy-6-[(5/6)-fluoresceinylthioureido]-BCD
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6-deoxy-6-[(5/6)-fluoresceinylthioureido]-BCD

Original price was: $1,795.00.Current price is: $895.00.

Catalog Number: B2027403 (100 mg)
6-deoxy-6-[(5/6)-fluoresceinylthioureido]-beta-cyclodextrin is a fluorescently labeled derivative of beta-cyclodextrin featuring a fluorescein fluorophore attached to the primary hydroxyl rim via a chemically stable thioureido linkage. This water-soluble macrocycle retains the host-guest complexation capabilities of cyclodextrins while enabling visualization of cellular uptake, membrane transport, and endosomal localization via fluorescence microscopy and flow cytometry. Supplied as a specialty reagent, it is intended strictly for laboratory R&D applications. Custom bulk amounts of this product are available upon request.

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Product Description

5/5 - (1 vote)

6-deoxy-6-[(5/6)-fluoresceinylthioureido]-BCD
Catalog number: B2027403
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 mg
Molecular Weight or Concentration: NA
Supplied as: Chemicals
Storage: 2-8 ˚C
Keywords: 6-deoxy-6-FITC-beta-cyclodextrin, Fluorescein-labeled beta-cyclodextrin, FITC-beta-cyclodextrin, 6-deoxy-6-FITC-BCD, Fluorescein-functionalized beta-cyclodextrin

References:
1. Veszelka, S., Mészáros, M., Porkoláb, G., Rusznyák, Á., Réti-Nagy, K. S., Deli, M. A., Vecsernyés, M., Bácskay, I., Váradi, J., & Fenyvesi, F. (2020). Cellular internalization and permeability of hydroxypropyl-β-cyclodextrin on brain capillary endothelial cells. Molecules, 25(18), 4283.
2. Prajapati, M., Christensen, G., Paquet-Durand, F., & Loftsson, T. (2021). Cytotoxicity of β-Cyclodextrins in Retinal Explants for Intravitreal Drug Formulations. Biomolecules, 11(8), 1194.
3. Loftsson, T., & Duchêne, D. (2007). Cyclodextrins and their pharmaceutical applications. International Journal of Pharmaceutics, 329(1-2), 1-11.
4. Szejtli, J. (1998). Introduction and general overview of cyclodextrin chemistry. Chemical Reviews, 98(5), 1743-1754.
5. Davis, M. E., & Brewster, M. E. (2004). Cyclodextrin-based pharmaceutics: past, present and future. Nature Reviews Drug Discovery, 3(12), 1023-1035.
6. Stella, V. J., & He, Q. (2008). Cyclodextrins. Toxicologic Pathology, 36(1), 30-42.
7. Vyas, A., Saraf, S., & Saraf, S. (2008). Cyclodextrin based novel drug delivery systems. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 62(1), 23-42.
8. Del Valle, E. M. (2004). Cyclodextrins and their uses: a review. Process Biochemistry, 39(9), 1033-1046.
9. Szente, L., & Szejtli, J. (2004). Highly soluble cyclodextrin derivatives: chemistry, properties, and trends in development. Advanced Drug Delivery Reviews, 56(9), 1229-1249.
10. Kurkov, S. V., & Loftsson, T. (2013). Cyclodextrins. International Journal of Pharmaceutics, 453(1), 167-180.
6-deoxy-6-[(5/6)-fluoresceinylthioureido]-BCD

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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