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4-Nitrophenyl-α-L-fucopyranoside

Original price was: $1,395.00.Current price is: $695.00.

Catalog Number: B2014944 (50 mg)
4-Nitrophenyl-α-L-fucopyranoside is a high quality chromogenic substrate that produces a soluble yellow chromophor for the colorimetric assay of α-L-fucosidase. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

4-Nitrophenyl-α-L-fucopyranoside
Catalog number: B2014944
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 mg
Molecular Weight or Concentration: 285.26 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20° C
Keywords: 4-Nitrophenyl-α-L- fucopyranoside, p-Nitrophenyl-α-L-fucoside, PNP-α-L-Fuc
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Gu G, Du Y, Hu H, Jin C. Synthesis of 2-chloro-4-nitrophenyl alpha-L-fucopyranoside: a substrate for alpha-L-fucosidase (AFU) Carbohydr Res. 2003 Jul 22;338(15):1603-7.
2: Megson ZA, Koerdt A, Schuster H, Ludwig R, Janesch B, Frey A, Naylor K, Wilson IB, Stafford GP, Messner P, Schäffer C. Characterization of an α-l-fucosidase from the periodontal pathogen Tannerella forsythia Virulence. 2015;6(3):282-92.
3: Wang JJ, Cao EH. Rapid kinetic rate assay of the serum alpha-L-fucosidase in patients with hepatocellular carcinoma by using a novel substrate Clin Chim Acta. 2004 Sep;347(1-2):103-9.
4: Jančaříková G, Herczeg M, Fujdiarová E, Houser J, Kövér KE, Borbás A, Wimmerová M, Csávás M. Synthesis of α-l-Fucopyranoside-Presenting Glycoclusters and Investigation of Their Interaction with Photorhabdus asymbiotica Lectin (PHL) Chemistry. 2018 Mar 15;24(16):4055-4068.
5: Dejter-Juszynski M, Flowers HM. Synthesis of 4-O-alpha-L-fucopyranosyl-L-fucose and methyl 4-O-beta-L-fucopyranosyl-alpha-L-fucopyranoside Carbohydr Res. 1975 May;41:308-12.
6: Cazarolli LH, Folador P, Moresco HH, Brighente IM, Pizzolatti MG, Silva FR. Mechanism of action of the stimulatory effect of apigenin-6-C-(2”-O-alpha-l-rhamnopyranosyl)-beta-L-fucopyranoside on 14C-glucose uptake Chem Biol Interact. 2009 May 15;179(2-3):407-12.
7: Cazarolli LH, Folador P, Moresco HH, Brighente IM, Pizzolatti MG, Silva FR. Stimulatory effect of apigenin-6-C-beta-L-fucopyranoside on insulin secretion and glycogen synthesis Eur J Med Chem. 2009 Nov;44(11):4668-73.
8: Gu G, Du Y, Hu H, Jin C. Synthesis of 2-chloro-4-nitrophenyl alpha-L-fucopyranoside: a substrate for alpha-L-fucosidase (AFU) Carbohydr Res. 2003 Jul 22;338(15):1603-7.
9: Sakai T, Tanemura Y, Itoh S, Fujimoto Y. Dodecyl α-L-rhamnopyranosyl-(1→2)-β-D-fucopyranoside derivatives from the glandular trichome exudate of Erodium pelargoniflorum Chem Biodivers. 2013 Jun;10(6):1099-108.
10: Perrella NN, Cantinha RS, Nakano E, Lopes AR. Characterization of α-L-fucosidase and other digestive hydrolases from Biomphalaria glabrata Acta Trop. 2015 Jan;141(Pt A):118-27.

Products Related to 4-Nitrophenyl-α-L-fucopyranoside can be found at Substrates

Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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