2,3:5,6-Di-O-isopropylidene-α-D-mannofuranose

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2,3:5,6-Di-O-isopropylidene-α-D-mannofuranose

Original price was: $795.00.Current price is: $395.00.

Catalog Number: B2027238 (1 g)
2,3:5,6-Di-O-isopropylidene-α-D-mannofuranose is a protected carbohydrate derivative widely utilized as a versatile chiral building block in organic synthesis and carbohydrate chemistry. The dual isopropylidene protecting groups selectively mask specific hydroxyl groups, enabling precise, site-specific functionalization of the D-mannose core. Supplied as a high-purity crystalline solid, this reagent is frequently applied in the development of complex oligosaccharides and glycoconjugates. Custom bulk amounts of this product are available upon request.

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Product Description

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2,3:5,6-Di-O-isopropylidene-α-D-mannofuranose
Catalog number: B2027238
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 g
Molecular Weight or Concentration: 260.29
Supplied as: Powder
Storage: NA
Keywords: D-Mannose diacetonide, Diaceton-alpha-D-mannofuranose, Diacetone-D-mannose, Diisopropylidenemannofuranose

References:
1. Kopitzki, S., & Hamann, H. J. (1996). Microscale synthesis of 2,3:5,6-di-O-isopropylidene-alpha-D-mannofuranose (“Diacetone Mannose”). Journal of Chemical Education, 73(8), A170.
2. Holden, H. M., Rayment, I., & Thoden, J. B. (2003). Structure and function of enzymes involved in the Leloir pathway for galactose metabolism. Journal of Biological Chemistry, 278(45), 43885-43888.
3. Frey, P. A. (1996). The Leloir pathway: a century of biochemistry and genetics. FASEB Journal, 10(4), 461-470.
4. Timson, D. J. (2016). The structural biology of galactosemia. International Journal of Molecular Sciences, 17(7), 1028.
5. Isselbacher, K. J., Anderson, E. P., Kurahashi, K., & Kalckar, H. M. (1956). Congenital galactosemia, a single enzymatic block in galactose metabolism. Science, 123(3198), 635-636.
6. Coelho, A. I., Berry, G. T., & Rubio-Gozalbo, M. E. (2015). Galactosemia: old metabolite, new implications. Journal of Inherited Metabolic Disease, 38(3), 431-443.
7. Ning, C., & Segal, S. (2000). Plasma galactose-1-phosphate in galactoseemic patients. Journal of Inherited Metabolic Disease, 23(1), 32-38.
8. Leloir, L. F. (1951). The enzymatic transformation of uridine diphosphate glucose into a galactose derivative. Archives of Biochemistry and Biophysics, 33(2), 186-190.
9. McCorvie, T. J., & Timson, D. J. (2011). The structural and physiological basis of galactosemia. Biochimica et Biophysica Acta – Molecular Basis of Disease, 1812(11), 1385-1398.
10. Fridovich-Keil, J. L. (2006). Galactosemia: the good, the bad, and the unknown. Journal of Cellular Physiology, 209(3), 701-705.
2,3:5,6-Di-O-isopropylidene-α-D-mannofuranose

Products Related to 2,3:5,6-Di-O-isopropylidene-α-D-mannofuranose can be found at Carbohydrates

Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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