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A new interesting article has been published in Clin Lab Med. 2019 Dec; 39(4):699-708. doi: 10.1016/j.cll.2019.07.014. Epub 2019 Oct 3. Review and titled:

The Future of Clinical Immunology Laboratory Testing.

Authors of this article are:

Allard-Chamard H, Mahajan VS.

A summary of the article is shown below:

For decades, autoantibody detection has comprised the bulk of clinical laboratory immunology. However, most immune disorders are caused by imbalances in both humoral and cellular immunity. Our knowledge of the immune system has grown exponentially, resulting in new treatment paradigms in immunology. Extensive functional characterization of lymphocyte subsets is routinely carried out in a research laboratories, facilitated by the emergence of high-dimensional analysis technologies for low cell numbers. It will not be long before these approaches enter the diagnostic realm. This chapter outlines emerging trends in laboratory immunology testing with a focus on deep immune profiling or high-dimensional testing modalities.Copyright © 2019 Elsevier Inc. All rights reserved.

Check out the article’s website on Pubmed for more information:

[link-preview url=https://www.ncbi.nlm.nih.gov/pubmed/31668279 forceshot=true]

This article is a good source of information and a good way to become familiar with topics such as: High-dimensional analysis; Immune function testing; Next-generation sequencing; Repertoire; Transcriptomics.

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