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Zinc (II) Protoporphyrin IX

Original price was: $1,395.00.Current price is: $695.00.

Catalog Number: B2016529 (10 mg)
Zinc (II) Protoporphyrin IX is a high quality compound that consists of a zinc ion coordinated to a protoporphyrin IX molecule. It is a synthetic analog of heme, which is an important component of hemoglobin in red blood cells. Zinc (II) Protoporphyrin IX is often used in research to study heme metabolism and its role in various biological processes. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

Zinc (II) Protoporphyrin IX
Catalog number: B2016529
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 mg
Molecular Weight or Concentration: N/A
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: Zinc (II) Protoporphyrin IX, ZnPP-9
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Bernardo-Seisdedos G, Schedlbauer A, Pereira-Ortuzar T, Mato JM, Millet O. Protoporphyrin IX Binds to Iron(II)-Loaded and to Zinc-Loaded Human Frataxin Life (Basel). 2023 Jan 12;13(1):222.
2: Wójtowicz H, Bielecki M, Wojaczyński J, Olczak M, Smalley JW, Olczak T. The Porphyromonas gingivalis HmuY haemophore binds gallium(iii), zinc(ii), cobalt(iii), manganese(iii), nickel(ii), and copper(ii) protoporphyrin IX but in a manner different to iron(iii) protoporphyrin IX Metallomics. 2013 Apr;5(4):343-51.
3: Miyazaki G, Morimoto H, Yun KM, Park SY, Nakagawa A, Minagawa H, Shibayama N. Magnesium(II) and zinc(II)-protoporphyrin IX’s stabilize the lowest oxygen affinity state of human hemoglobin even more strongly than deoxyheme J Mol Biol. 1999 Oct 8;292(5):1121-36.
4: Luo GF, Biniuri Y, Chen WH, Wang J, Neumann E, Marjault HB, Nechushtai R, Winkler M, Happe T, Willner I. Modelling Photosynthesis with Zn(II)_Protoporphyrin All-DNA G-Quadruplex/Aptamer Scaffolds Angew Chem Int Ed Engl. 2020 Jun 2;59(23):9163-9170.
5: Zhang P, Ouyang Y, Sohn YS, Fadeev M, Karmi O, Nechushtai R, Stein I, Pikarsky E, Willner I. miRNA-Guided Imaging and Photodynamic Therapy Treatment of Cancer Cells Using Zn(II)-Protoporphyrin IX-Loaded Metal-Organic Framework Nanoparticles ACS Nano. 2022 Feb 22;16(2):1791-1801.
6: Zhang Z, Sharon E, Freeman R, Liu X, Willner I. Fluorescence detection of DNA, adenosine-5′-triphosphate (ATP), and telomerase activity by zinc(II)_protoporphyrin IX/G-quadruplex labels Anal Chem. 2012 Jun 5;84(11):4789-97.
7: Hirano C, Imae T. Electrochemical properties of protoporphyrin IX zinc(II) films J Colloid Interface Sci. 2004 Dec 15;280(2):478-83.
8: Scott J, Quirke JM, Vreman HJ, Stevenson DK, Downum KR. Metalloporphyrin phototoxicity J Photochem Photobiol B. 1990 Nov;7(2-4):149-57.
9: Komatsu T. Protein-based nanotubes for biomedical applications Nanoscale. 2012 Mar 21;4(6):1910-8.
10: Nowis D, Bugajski M, Winiarska M, Bil J, Szokalska A, Salwa P, Issat T, Was H, Jozkowicz A, Dulak J, Stoklosa T, Golab J. Zinc protoporphyrin IX, a heme oxygenase-1 inhibitor, demonstrates potent antitumor effects but is unable to potentiate antitumor effects of chemotherapeutics in mice BMC Cancer. 2008 Jul 11;8:197.

Products Related to Zinc (II) Protoporphyrin IX can be found at Chemicals

Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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