Yersinia YopH Protein Active

Description

Yersinia YopH Protein Active
Catalog number: B2014397
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 μg
Molecular Weight or Concentration: 77.4 kDa
Supplied as: N/A
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: YopH Protein, active
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Tamilvanan T, Hopper W. Biologically active ligands for yersinia outer protein H (YopH): feature based pharmacophore screening, docking and molecular dynamics studies Comb Chem High Throughput Screen. 2014;17(7):579-95.
2: Hamid N, Gustavsson A, Andersson K, McGee K, Persson C, Rudd CE, F_llman M. YopH dephosphorylates Cas and Fyn-binding protein in macrophages Microb Pathog. 1999 Oct;27(4):231-42.
3: Rocha RF, Martins PGA, D’Muniz Pereira H, Brando-Neto J, Thiemann OH, Terenzi H, Menegatti ACO. Crystal structure of the Cys-NO modified YopH tyrosine phosphatase Biochim Biophys Acta Proteins Proteom. 2022 Mar 1;1870(3):140754.
4: Sun JP, Wu L, Fedorov AA, Almo SC, Zhang ZY. Crystal structure of the Yersinia protein-tyrosine phosphatase YopH complexed with a specific small molecule inhibitor J Biol Chem. 2003 Aug 29;278(35):33392-9.
5: Moise G, Gallup NM, Alexandrova AN, Hengge AC, Johnson SJ. Conservative tryptophan mutants of the protein tyrosine phosphatase YopH exhibit impaired WPD-loop function and crystallize with divanadate esters in their active sites Biochemistry. 2015 Oct 27;54(42):6490-500.
6: Yuan M, Deleuil F, F_llman M. Interaction between the Yersinia tyrosine phosphatase YopH and its macrophage substrate, Fyn-binding protein, Fyb J Mol Microbiol Biotechnol. 2005;9(3-4):214-23.
7: Deleuil F, Mogemark L, Francis MS, Wolf-Watz H, F_llman M. Interaction between the Yersinia protein tyrosine phosphatase YopH and eukaryotic Cas/Fyb is an important virulence mechanism Cell Microbiol. 2003 Jan;5(1):53-64.
8: Brando TA, Johnson SJ, Hengge AC. The molecular details of WPD-loop movement differ in the protein-tyrosine phosphatases YopH and PTP1B Arch Biochem Biophys. 2012 Sep 1;525(1):53-9.
9: Hogan M, Bahta M, Cherry S, Lountos GT, Tropea JE, Zhao BM, Burke TR Jr, Waugh DS, Ulrich RG. Biomolecular Interactions of small-molecule inhibitors affecting the YopH protein tyrosine phosphatase Chem Biol Drug Des. 2013 Mar;81(3):323-33.
10: Kuban-Jankowska A, Sahu KK, Gorska M, Niedzialkowski P, Tuszynski JA, Ossowski T, Wozniak M. Aurintricarboxylic acid structure modifications lead to reduction of inhibitory properties against virulence factor YopH and higher cytotoxicity World J Microbiol Biotechnol. 2016 Oct;32(10):163.

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