Yeast-Derived Uricase

Description

Yeast-Derived Uricase
Catalog number: B2013361
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 U
Molecular Weight or Concentration: 2U/mg
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Yeast-Derived Uricase
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Biggers K, Scheinfeld N. Pegloticase, a polyethylene glycol conjugate of uricase for the potential intravenous treatment of gout Curr Opin Investig Drugs. 2008 Apr;9(4):422-9.
2: Liu D, Yang P, Wang F, Wang C, Chen L, Ye S, Dramou P, Chen J, He H. Study on performance of mimic uricase and its application in enzyme-free analysis Anal Bioanal Chem. 2021 Nov;413(26):6571-6580.
3: Schlesinger N, Lipsky PE. Pegloticase treatment of chronic refractory gout: Update on efficacy and safety Semin Arthritis Rheum. 2020 Jun;50(3S):S31-S38.
4: Hao Y, Li H, Cao Y, Chen Y, Lei M, Zhang T, Xiao Y, Chu B, Qian Z. Uricase and Horseradish Peroxidase Hybrid CaHPO₄ Nanoflower Integrated with Transcutaneous Patches for Treatment of Hyperuricemia J Biomed Nanotechnol. 2019 May 1;15(5):951-965.
5: GREENE RC, MITCHELL HK. Uricase in Neurospora crassa Arch Biochem Biophys. 1957 Aug;70(2):603-13.
6: Li Z, Hoshino Y, Tran L, Gaucher EA. Phylogenetic Articulation of Uric Acid Evolution in Mammals and How It Informs a Therapeutic Uricase Mol Biol Evol. 2022 Jan 7;39(1):msab312.
7: Li H, Huo J, Sun D, Guo Y, Jiang L, Zhang H, Shi X, Zhao Z, Zhou J, Hu C, Zhang C. Determination of PEGylation homogeneity of polyethylene glycol-modified canine uricase Electrophoresis. 2021 Mar;42(6):693-699.
8: Zhao R, Li Z, Sun Y, Ge W, Wang M, Liu H, Xun L, Xia Y. Engineered Escherichia coli Nissle 1917 with urate oxidase and an oxygen-recycling system for hyperuricemia treatment Gut Microbes. 2022 Jan-Dec;14(1):2070391.
9: Zhou Z, Zhao H, Zhang L, Xie Q, Liu Q, Tong M, Yu X, Xiong S. Soluble expression of bioactive recombinant porcine-human chimeric uricase mutant employing MBP-SUMO fusion system Protein Expr Purif. 2022 Jan;189:105978.
10: Tork SE, Aly MM, Al-Fattani SQ. A new uricase from Bacillus cereus SKIII: Characterization, gene identification and genetic improvement Int J Biol Macromol. 2020 Dec 15;165(Pt B):3135-3144.

Products Related to Yeast-Derived Uricase can be found at Enzymes