Uroguanylin (Highly Pure)

Description

Uroguanylin (Highly Pure)
Catalog number: B2014258
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.1 mg
Molecular Weight or Concentration: 1667.86 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu [Disulfide bridges: 4–12, 7–15]
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Folgueira C, Barja-Fernandez S, Gonzalez-Saenz P, Pena-Leon V, Castelao C, Ruiz-Pion M, Casanueva FF, Nogueiras R, Seoane LM. Uroguanylin: a new actor in the energy balance movie J Mol Endocrinol. 2018 Feb;60(2):R31-R38.
2: Parikh K, Antanaviciute A, Fawkner-Corbett D, Jagielowicz M, Aulicino A, Lagerholm C, Davis S, Kinchen J, Chen HH, Alham NK, Ashley N, Johnson E, Hublitz P, Bao L, Lukomska J, Andev RS, Bjrklund E, Kessler BM, Fischer R, Goldin R, Koohy H, Simmons A. Colonic epithelial cell diversity in health and inflammatory bowel disease Nature. 2019 Mar;567(7746):49-55.
3: Rahbi H, Narayan H, Jones DJ, Ng LL. The uroguanylin system and human disease Clin Sci (Lond). 2012 Dec;123(12):659-68.
4: Forte LR Jr. Uroguanylin and guanylin peptides: pharmacology and experimental therapeutics Pharmacol Ther. 2004 Nov;104(2):137-62.
5: Zeng C, Xia T, Zheng S, Liang L, Chen Y. Synergistic Effect of Uroguanylin and D(1) Dopamine Receptors on Sodium Excretion in Hypertension J Am Heart Assoc. 2022 Mar 15;11(6):e022827.
6: Forte LR, Fan X, Hamra FK. Salt and water homeostasis: uroguanylin is a circulating peptide hormone with natriuretic activity Am J Kidney Dis. 1996 Aug;28(2):296-304.
7: Busslinger GA, Weusten BLA, Bogte A, Begthel H, Brosens LAA, Clevers H. Human gastrointestinal epithelia of the esophagus, stomach, and duodenum resolved at single-cell resolution Cell Rep. 2021 Mar 9;34(10):108819.
8: Sindi A, Schlatter E. Mechanisms of action of uroguanylin and guanylin and their role in salt handling Nephrol Dial Transplant. 2006 Nov;21(11):3007-12.
9: Folgueira C, Barja-Fernndez S, Gonzalez-Saenz P, Castelao C, Vzquez-Cobela R, Pena-Leon V, Ruiz-Pion M, Casanueva FF, Dieguez C, Leis R, Nogueiras R, Seoane LM. Circulating Pro-Uroguanylin Levels In Children And Their Relation To Obesity, Sex And Puberty Sci Rep. 2018 Sep 28;8(1):14541.
10: Sindi A, Schlatter E. Cellular effects of guanylin and uroguanylin J Am Soc Nephrol. 2006 Mar;17(3):607-16.

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