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Thyroid Hormone Receptor β-1 Antibody

$1,250.00

Catalog Number: B2010534 (100 ug)
Thyroid Hormone Receptor β-1 Antibody is a highly pure rabbit polyclonal antibody to human thyroid receptor B-1. This product has been used as molecular tool for various studies related to the physiology of the Thyroid hormone. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2010534 Categories: ,

Description

Thyroid Hormone Receptor β-1 Antibody
Catalog number: B2010534
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 150 kDa
Supplied as: Solution
Applications: molecular tool for various studies related to the physiology of the Thyroid hormone
Storage: −20°C
Keywords: Thyroid hormone receptor beta, Nuclear receptor subfamily 1 group A member 2, c-erbA-2, c-erbA-beta, thyroid receptor antibody
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Deveau C, Jiao X, Suzuki SC, Krishnakumar A, Yoshimatsu T, Hejtmancik JF,
Nelson RF. Thyroid hormone receptor beta mutations alter photoreceptor
development and function in Danio rerio (zebrafish). PLoS Genet. 2020 Jun
22;16(6):e1008869.

2: Delitala AP, Capobianco G, Cherchi PL, Dessole S, Delitala G. Thyroid
function and thyroid disorders during pregnancy: a review and care pathway. Arch
Gynecol Obstet. 2019 Feb;299(2):327-338.

3: Nakaya H, Tatematsu KI, Sezutsu H, Kuwabara N, Koibuchi N, Takeda S.
Secretory expression of thyroid hormone receptor using transgenic silkworms and
its DNA binding activity. Protein Expr Purif. 2020 Dec;176:105723.

4: Olateju TO, Vanderpump MP. Thyroid hormone resistance. Ann Clin Biochem. 2006
Nov;43(Pt 6):431-40.

5: Ditsch N, Toth B, Himsl I, Lenhard M, Ochsenkühn R, Friese K, Mayr D, Jeschke
U. Thyroid hormone receptor (TR)alpha and TRbeta expression in breast cancer.
Histol Histopathol. 2013 Feb;28(2):227-37.

6: Morshed SA, Ma R, Latif R, Davies TF. Biased signaling by thyroid-stimulating
hormone receptor-specific antibodies determines thyrocyte survival in
autoimmunity. Sci Signal. 2018 Jan 23;11(514):eaah4120.

7: Bhat MK, McPhie P, Cheng SY. Interaction of thyroid hormone nuclear receptor
with antibody: characterization of the thyroid hormone binding site. Biochem
Biophys Res Commun. 1995 May 16;210(2):464-71.

8: Zerek-Mełeń G, Zylińska K, Fryczak J, Mucha S, Stepień H. Influence of
interleukin 1 and antihuman interleukin 1 receptor antibody on the growth and
function of the thyroid gland in rats. Eur J Endocrinol. 1994 Nov;131(5):531-4.

9: Bhat MK, Parkison C, McPhie P, Liang CM, Cheng SY. Conformational changes of
human beta 1 thyroid hormone receptor induced by binding of 3,3′,5-triiodo-L-
thyronine. Biochem Biophys Res Commun. 1993 Aug 31;195(1):385-92.

10: Macchia E, Nakai A, Janiga A, Sakurai A, Fisfalen ME, Gardner P, Soltani K,
DeGroot LJ. Characterization of site-specific polyclonal antibodies to c-erbA
peptides recognizing human thyroid hormone receptors alpha 1, alpha 2, and beta
and native 3,5,3′-triiodothyronine receptor, and study of tissue distribution of
the antigen. Endocrinology. 1990 Jun;126(6):3232-9.

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