Thioflavin T (Highly Pure)


Catalog Number: B2011272 (100 mg)
Thioflavin T (Highly Pure) is a high quality benzothiazole dye thioflavin T that is used to stain amyloid senile plaques containing the βA4 peptide. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Thioflavin T (Highly Pure)
Catalog number: B2011272
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 mg
Molecular Weight or Concentration: 318.9 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: ThT
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Biancalana M, Koide S. Molecular mechanism of Thioflavin_T binding to amyloid fibrils Biochim Biophys Acta. 2010 Jul;1804(7):1405-12.
2: Khurana R, Coleman C, Ionescu-Zanetti C, Carter SA, Krishna V, Grover RK, Roy R, Singh S. Mechanism of thioflavin _ binding to amyloid fibrils J Struct Biol. 2005 Sep;151(3):229-38.
3: Verma S, Ravichandiran V, Ranjan N. Beyond amyloid proteins: Thioflavin_T in nucleic acid recognition Biochimie. 2021 Nov;190:111-123.
4: Hudson SA, Ecroyd H, Kee TW, Carver JA. The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds FEBS J. 2009 Oct;276(20):5960-72.
5: Schlein M. Insulin Formulation Characterization-the Thioflavin T Assays AAPS J. 2017 Mar;19(2):397-408.
6: Sancataldo G, Anselmo S, Vetri V. Phasor-FLIM analysis of Thioflavin_T self-quenching in Concanavalin amyloid fibrils Microsc Res Tech. 2020 Jul;83(7):811-816.
7: Ziaunys M, Smirnovas V. Additional Thioflavin-T Binding Mode in Insulin Fibril Inner Core Region J Phys Chem B. 2019 Oct 17;123(41):8727-8732.
8: Damase TR, Islam MM, Shipley M, Allen PB. Thioflavin_T as a noncovalent reporter for a label-free, non-enzymatic, catalytic DNA amplifier Methods Appl Fluoresc. 2020 Jul 20;8(4):045001.
9: Son G, Lee SH, Wang D, Park CB. Thioflavin_T-Amyloid Hybrid Nanostructure for Biocatalytic Photosynthesis Small. 2018 Oct;14(40):e1801396.
10: Hanczyc P, Rajchel-Mieldzioć P, Feng B, Fita P. Identification of Thioflavin T Binding Modes to DNA: A Structure-Specific Molecular Probe for Lasing Applications J Phys Chem Lett. 2021 Jun 10;12(22):5436-5442.

Products Related to Thioflavin T (Highly Pure) can be found at Dyes

Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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