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T1/ST2 (IL-33 R) Mouse, Monoclonal Antibody

Original price was: $2,595.00.Current price is: $1,295.00.

Catalog Number: B2026974 (0.5 mL)
The T1/ST2 (IL-33 R) monoclonal antibody is a rat IgG1 isotype tool designed to identify and purify murine T helper 2 (Th2) and mast cells. It binds to the ST2 receptor. Custom bulk amounts of this product are available upon request.

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SKU: B2026974 Category: Tag:

Product Description

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T1/ST2 (IL-33 R) Mouse, Monoclonal Antibody
Catalog number: B2026974
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.5 mL
Molecular Weight or Concentration: NA
Supplied as: Solution
Storage: −20°C
Keywords: IL-33 R, IL-33Ra, IL-1 R4, IL1R4, IL1RL1, T1, ST2, DER4, Fit-1, Ly84, ST2L, ST2V, Growth stimulation-expressed protein 2, Interleukin 1 receptor-like 1

References:
1. Schmitz, J., Owyang, A., Oldham, E., Song, Y., Murphy, E., McClanahan, T. K., Zurawski, G., Moshrefi, M., Qin, J., Li, X., et al. (2005). IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity, 23(5), 479-490.
2. Chackerian, A. A., Oldham, E. R., Murphy, E. E., Schmitz, J., Pflanz, S., & Kastelein, R. A. (2007). IL-1 receptor accessory protein and ST2 comprise the IL-33 receptor complex. Journal of Immunology, 179(4), 2551-2555.
3. Matta, B. M., Lott, J. M., Mathews, L. R., Liu, Q., Rosborough, B. R., Blazar, B. R., & Turnquist, H. R. (2014). IL-33 is an unconventional alarmin that stimulates IL-2 secretion by dendritic cells to selectively expand IL-33R/ST2+ regulatory T cells. Journal of Immunology, 193(8), 4010-4020.
4. Tominaga, S., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., & Tetsuka, T. (1992). Molecular cloning of the murine ST2 gene. Biochimica et Biophysica Acta, 1171(2), 215-218.
5. Brint, E. K., Fitzgerald, K. A., Smith, P., Ning, Y., Kastelein, R. A., O’Neill, L. A., & Xu, D. (2004). ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nature Immunology, 5(4), 373-379.
6. Lecart, S., Lecointe, N., Subramaniam, A., Chavany, G., Cassard, L., Boulay, V., Ryffel, B., Bonnefoy, J. Y., & Gauchat, J. F. (2002). Activated, but not resting Th2 cells, in collaboration with periodic acid-Schiff-positive cells, produce soluble ST2 and its biogenesis is IL-4 dependent. European Journal of Immunology, 32(10), 2979-2987.
7. Palmer, G., Talabot-Ayer, D., Lamacchia, C., Toy, D., Seemayer, C. A., Viatte, S., Finck, B. K., Smith, D. E., Huang, S., & Gabay, C. (2008). Inhibition of imiquimod-induced psoriasis-like skin inflammation by the soluble IL-33 receptor (sST2) in mice. Cytokine, 42(3), 358-364.
8. Verri, W. A. Jr., Guerrero, A. T., Melo, P. H., Almeida, S. C., Queiroz-Cunha, P. M., Ferreira, S. H., Poole, S., & Cunha, F. Q. (2008). IL-33 mediates antigen-induced cutaneous and articular hypernociception in mice. Proceedings of the National Academy of Sciences, 105(7), 2723-2728.
9. Miller, A. M., Xu, D., Asquith, D. L., Denby, L., Li, Y., Sattar, N., Baker, A. H., & Liew, F. Y. (2008). IL-33 reduces atherosclerosis in mice by enhancing Th2 responses. Journal of Experimental Medicine, 205(2), 339-346.
10. Allakhverdi, Z., Smith, D. E., Comeau, M. R., & Delespesse, G. (2007). Cutting edge: The ST2 ligand IL-33 potently activates and drives maturation of human mast cells. Journal of Immunology, 179(4), 2051-2054.
T1/ST2 (IL-33 R) Mouse, Monoclonal Antibody

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
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