T1/ST2 (IL-33 R) Mouse, Monoclonal Antibody, Biotinylated
Original price was: $2,795.00.$1,395.00Current price is: $1,395.00.
Catalog Number: B2026975 (0.5 mL)
T1/ST2 (IL-33 R) Mouse, Monoclonal Antibody, Biotinylated is specifically designed for the identification and purification of murine Th2 cells and mast cells by targeting the T1/ST2 (IL-33 receptor) protein. It recognizes the membrane-anchored T1M protein on the cell surface and can also detect the soluble T1S protein isoform. Custom bulk amounts of this product are available upon request.
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Product Description
T1/ST2 (IL-33 R) Mouse, Monoclonal Antibody, Biotinylated
Catalog number: B2026975
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.5 mL
Molecular Weight or Concentration: NA
Supplied as: Solution
Storage: −20°C
Keywords: DER4, Fit-1, IL-1 R4, IL-1R4, IL-1RL1, IL-33 R, IL-33R, IL1R4, IL1RL1, IL33R, Ly84, ST2, ST2L, ST2V, T1, T1/ST2, Interleukin-1 receptor-like 1, Interleukin-33 receptor alpha chain, Lymphocyte antigen 84, Protein ST2, Protein T1, Serum stimulation-2, Growth stimulation expressed gene 2
References:
“1. Schmitz J, Owyang A, Oldham E, et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity. 2005;23(5):479-490.
2. Tominaga S. A putative RNA binding protein gene (SST2) is induced in murine BALB/c-3T3 cells by serum and growth factors. FEBS Letters. 1989;258(2):301-304.
3. Kakkar R, Lee RT. The IL-33/ST2 pathway: therapeutic target and novel biomarker. Nature Reviews Drug Discovery. 2008;7(10):827-840.
4. Liew FY, Girard JP, Turnquist HR. Interleukin-33 in health and disease. Nature Reviews Immunology. 2016;16(11):676-689.
5. Lohning M, Stroehmann A, Coyle AJ, et al. T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function. Proceedings of the National Academy of Sciences. 1998;95(12):6930-6935.
6. Lingel A, Weiss TM, Niebuhr M, et al. Structure of IL-33 and its interaction with the ST2 and IL-1RAcP receptors – insight into heterotrimeric IL-1 signaling complexes. Structure. 2009;17(10):1398-1410.
7. Miossec P, Korn T, Kuchroo VK. Interleukin-17 and type 17 helper T cells. New England Journal of Medicine. 2009;361(9):888-898.
8. Oboki K, Ohno T, Kajiwara N, et al. IL-33 is a crucial amplifier of innate rather than acquired immunity. Proceedings of the National Academy of Sciences. 2010;107(43):18581-18586.
9. Palmer G, Gabay C. Interleukin-33 biology with special focus on embryogenesis and angiogenesis. Swiss Medical Weekly. 2011;141:w13217.
10. Sanada S, Hakuno D, Higgins LJ, et al. IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system. Journal of Clinical Investigation. 2007;117(6):1538-1549.”
T1/ST2 (IL-33 R) Mouse, Monoclonal Antibody, Biotinylated
Products Related to T1/ST2 (IL-33 R) Mouse, Monoclonal Antibody, Biotinylated can be found at Antibodies
Additional Information
| Weight | 0.15 oz |
|---|---|
| Dimensions | 2 × 0.5 × 0.5 in |
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