Src Kinase Reaction Buffer Solution

Product Description

Src Kinase Reaction Buffer
Catalog number: B2010134
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 4 x 1 mL
pH: 7.2
Supplied as: Ready-to-use solution
Appearance: Clear solution
Applications: optimized buffer for use in kinase assays.
Storage: −20°C
Keywords: Kinase reaction buffer, kinase assay buffer, kinase reaction solution
Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.

References:
1: Roskoski R Jr. Src protein-tyrosine kinase structure, mechanism, and small
molecule inhibitors. Pharmacol Res. 2015 Apr;94:9-25.

2: Roskoski R Jr. Src kinase regulation by phosphorylation and
dephosphorylation. Biochem Biophys Res Commun. 2005 May 27;331(1):1-14.

3: Roskoski R Jr. Src protein-tyrosine kinase structure and regulation. Biochem
Biophys Res Commun. 2004 Nov 26;324(4):1155-64.

4: Creedon H, Brunton VG. Src kinase inhibitors: promising cancer therapeutics?
Crit Rev Oncog. 2012;17(2):145-59.

5: Taskinen B, Ferrada E, Fowler DM. Early emergence of negative regulation of
the tyrosine kinase Src by the C-terminal Src kinase. J Biol Chem. 2017 Nov
10;292(45):18518-18529.

6: Shah NH, Amacher JF, Nocka LM, Kuriyan J. The Src module: an ancient scaffold
in the evolution of cytoplasmic tyrosine kinases. Crit Rev Biochem Mol Biol.
2018 Oct;53(5):535-563.

7: Keenan S, Wetherill SJ, Ugbode CI, Chawla S, Brackenbury WJ, Evans GJ.
Inhibition of N1-Src kinase by a specific SH3 peptide ligand reveals a role for
N1-Src in neurite elongation by L1-CAM. Sci Rep. 2017 Feb 21;7:43106.

8: Kim NG, Gumbiner BM. Adhesion to fibronectin regulates Hippo signaling via
the FAK-Src-PI3K pathway. J Cell Biol. 2015 Aug 3;210(3):503-15.

9: Manea SA, Fenyo IM, Manea A. c-Src tyrosine kinase mediates high glucose-
induced endothelin-1 expression. Int J Biochem Cell Biol. 2016 Jun;75:123-30.

10: Elsberger B. Translational evidence on the role of Src kinase and activated
Src kinase in invasive breast cancer. Crit Rev Oncol Hematol. 2014
Mar;89(3):343-51.

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