SARS-CoV-2 NSP8 Protein

Product Description

SARS-CoV-2 NSP8 Protein
Catalog number: B2013087
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 22.0 kDa
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: SARS-CoV-2 NSP8
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
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2: Gao Y, Yan L, Huang Y, Liu F, Zhao Y, Cao L, Wang T, Sun Q, Ming Z, Zhang L, Ge J, Zheng L, Zhang Y, Wang H, Zhu Y, Zhu C, Hu T, Hua T, Zhang B, Yang X, Li J, Yang H, Liu Z, Xu W, Guddat LW, Wang Q, Lou Z, Rao Z. Structure of the RNA-dependent RNA polymerase from COVID-19 virus Science. 2020 May 15;368(6492):779-782.
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5: Sarma H, Jamir E, Sastry GN. Protein-protein interaction of RdRp with its co-factor NSP8 and NSP7 to decipher the interface hotspot residues for drug targeting: A comparison between SARS-CoV-2 and SARS-CoV J Mol Struct. 2022 Jun 5;1257:132602.
6: Yeo G, Xiang J, Mueller J, Luo EC, Yee B, Schafer D, Schmok J, Tan F, Rothamel K, McVicar R, Kwong E, Croker B, Jones K, Her HL, Chen CY, Vu A, Jin W, Park S, Le P, Brennan K, Kofman E, Li Y, Tankka A, Dong K, Song Y, Clark A, Carlin A, Nostrand EV, Leibel S. Discovery and functional interrogation of SARS-CoV-2 protein-RNA interactions Res Sq. 2022 Mar 17:rs.3.rs-1394331.
7: Xiang JS, Mueller JR, Luo EC, Yee BA, Schafer D, Schmok JC, Tan FE, Rothamel K, McVicar RN, Kwong EM, Jones KL, Her HL, Chen CY, Vu AQ, Jin W, Park SS, Le P, Brannan KW, Kofman ER, Li Y, Tankka AT, Dong KD, Song Y, Carlin AF, Van Nostrand EL, Leibel SL, Yeo GW. Discovery and functional interrogation of SARS-CoV-2 protein-RNA interactions bioRxiv. 2022 Feb 23:2022.02.21.481223.
8: Mutlu O, Ugurel OM, Sariyer E, Ata O, Inci TG, Ugurel E, Kocer S, Turgut-Balik D. Targeting SARS-CoV-2 Nsp12/Nsp8 interaction interface with approved and investigational drugs: an in silico structure-based approach J Biomol Struct Dyn. 2022 Feb;40(2):918-930.
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