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Rheumatoid Factor Removal Kit for Serum and Plasma

$695.00

Catalog Number: K2010013 (10 reactions)
Rheumatoid Factor Removal Kit is the only kit designed to deplete human serum or plasma from Rheumatoid Factors (RF). This kit uses a proprietary solution to specifically and easily capture RF. Simply add serum or plasma to the provided solution, vortex, spindown and recover your RF-free sample. For Research Use Only. Not for Diagnostic Use. Custom bulk orders of this product are available upon request.

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SKU: K2010013 Categories: ,

Description

Rheumatoid Factor Removal Kit for Serum and Plasma
Catalog number: K2010013
Lot number: Batch Dependent
Expiration Date: Batch dependent
Size: 10 reactions (enough for processing 10 samples of 1 mL each)
Storage: 2-8C
Supplied as: Ready-to-use kit

Applications: Rheumatoid Factor (RF) remains a major source of interference in immunoassays (despite claims to the contrary made by manufacturers). Using a propriety solution, this kit is designed to deplete human serum or plasma from Rheumatoid Factor. Simply add serum or plasma to the provided solution, vortex, spindown and recover an RF-free sample. For Research Use Only. Not for diagnostic use.

Keywords: RF Depletion Kit, RF Removal Kit, RF Suppression Kit, RF Blocking

References:

1: Maibom-Thomsen SL, Trier NH, Holm BE, Hansen KB, Rasmussen MI, Chailyan A,
Marcatili P, Højrup P, Houen G. Immunoglobulin G structure and rheumatoid factor
epitopes. PLoS One. 2019 Jun 14;14(6):e0217624.

2: Shmerling RH, Delbanco TL. The rheumatoid factor: an analysis of clinical
utility. Am J Med. 1991 Nov;91(5):528-34.

3: Kalsi J, Isenberg D. Rheumatoid factor: primary or secondary event in the
pathogenesis of RA? Int Arch Allergy Immunol. 1993;102(3):209-15.

4: Johnson PM, Faulk WP. Rheumatoid factor: its nature, specificity, and
production in rheumatoid arthritis. Clin Immunol Immunopathol. 1976
Nov;6(3):414-30.

5: Beduleva L, Stolyarova E, Sidorov A, Khramova T, Terentiev A, Menshikov I,
Abisheva N, Snigiryev A, Fomina K. Immunoglobulin G amplifies the production of
regulatory rheumatoid factor in vitro through idiotype-anti-idiotype
interactions. J Immunoassay Immunochem. 2020;41(2):219-230.

6: Eichenfield AH, Athreya BH, Doughty RA, Cebul RD. Utility of rheumatoid
factor in the diagnosis of juvenile rheumatoid arthritis. Pediatrics. 1986
Sep;78(3):480-4.

7: Chinnadayyala SR, Park J, Abbasi MA, Cho S. Label-free electrochemical
impedimetric immunosensor for sensitive detection of IgM rheumatoid factor in
human serum. Biosens Bioelectron. 2019 Oct 15;143:111642.

8: Shiroishi M, Ito Y, Shimokawa K, Lee JM, Kusakabe T, Ueda T. Structure-
function analyses of a stereotypic rheumatoid factor unravel the structural
basis for germline-encoded antibody autoreactivity. J Biol Chem. 2018 May
4;293(18):7008-7016.

9: Hamilton RG. Rheumatoid factor interference in immunological methods. Monogr
Allergy. 1989;26:27-44.

Rheumatoid Factor Removal Kit for Serum and Plasma: Research Kits

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