Retinyl acetate/RAMEB Complex

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Retinyl acetate/RAMEB Complex
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Retinyl acetate/RAMEB Complex

Original price was: $1,795.00.Current price is: $895.00.

Catalog Number: B2027421 (100 mg)
Retinyl acetate/RAMEB Complex is a host-guest inclusion complex comprising the lipophilic vitamin A derivative retinyl acetate encapsulated within randomly methylated beta-cyclodextrin (RAMEB). The macrocyclic cyclodextrin cavity masks the hydrophobic retinyl acetate, significantly enhancing its aqueous solubility, chemical stability, and bioavailability for research and formulation applications. It is provided as a specialty fine chemical reagent suitable for targeted delivery and laboratory studies. Custom bulk amounts of this product are available upon request.

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Product Description

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Retinyl acetate/RAMEB Complex
Catalog number: B2027421
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 mg
Molecular Weight or Concentration: NA
Supplied as: Chemicals
Storage: RT
Keywords: Retinyl acetate/Randomly methylated beta-cyclodextrin complex, Retinyl acetate/Methylated beta-cyclodextrin complex

References:
1. Valero, M., & Espada, I. (2003). Complexation of retinyl acetate with beta-cyclodextrin and its derivatives in aqueous solution. International Journal of Pharmaceutics, 258(1-2), 163-171.
2. Loftsson, T., & Duchêne, D. (2007). Cyclodextrins and their pharmaceutical applications. International Journal of Pharmaceutics, 329(1-2), 1-11.
3. Szejtli, J. (1998). Introduction and general overview of cyclodextrin chemistry. Chemical Reviews, 98(5), 1743-1754.
4. Szente, L., & Szejtli, J. (2004). Highly soluble cyclodextrin derivatives: chemistry, properties, and trends in development. Advanced Drug Delivery Reviews, 56(9), 1229-1249.
5. Tian, B. R., Liu, Y., & Zhang, H. Y. (2020). Randomly methylated cyclodextrins as versatile solubilizers and carriers in drug delivery. Carbohydrate Polymers, 240, 116285.
6. Uekama, K., Hirayama, F., & Irie, T. (1998). Cyclodextrin-invoked bioavailability enhancement of drugs. Chemical Reviews, 98(5), 2045-2076.
7. Pinho, E., Grootveld, M., Soares, G., & Henriques, M. (2014). Cyclodextrins as encapsulation agents for bioactive compounds. Carbohydrate Polymers, 101, 121-135.
8. Davis, M. E., & Brewster, M. E. (2004). Cyclodextrin-based pharmaceutics: past, present and future. Nature Reviews Drug Discovery, 3(12), 1023-1035.
9. Jansook, P., Ogawa, N., & Loftsson, T. (2018). Cyclodextrins: structure, physicochemical properties and pharmaceutical applications. International Journal of Pharmaceutics, 535(1-2), 272-284.
10. Kurkov, S. V., & Loftsson, T. (2013). Cyclodextrins. International Journal of Pharmaceutics, 453(1), 167-180.
Retinyl acetate/RAMEB Complex

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
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