Recombinant Human Chromogranin A Protein


Catalog Number: B2012594 (20 ug)
Recombinant Human Chromogranin A Protein is a high quality recombinant human CHGA produced in E. coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Recombinant Human Chromogranin A Protein
Catalog number: B2012594
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 20 ug
Molecular Weight or Concentration: 12.8 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: Chromogranin A
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Taupenot L, Remacle JE, Helle KB, Aunis D, Bader MF. Recombinant human chromogranin A: expression, purification and characterization of the N-terminal derived peptides Regul Pept. 1995 Mar 7;56(1):71-88.
2: Cappello S, Angelone T, Tota B, Pagliaro P, Penna C, Rastaldo R, Corti A, Losano G, Cerra MC. Human recombinant chromogranin A-derived vasostatin-1 mimics preconditioning via an adenosine/nitric oxide signaling mechanism Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H719-27.
3: Okasha H, Samir S, Nasr SM. Purified recombinant human Chromogranin A N46 peptide with remarkable anticancer effect on human colon cancer cells Bioorg Chem. 2021 Oct;115:105266.
4: Parmer RJ, Xi XP, Wu HJ, Helman LJ, Petz LN. Secretory protein traffic. Chromogranin A contains a dominant targeting signal for the regulated pathway J Clin Invest. 1993 Aug;92(2):1042-54.
5: Helman LJ, Gazdar AF, Park JG, Cohen PS, Cotelingam JD, Israel MA. Chromogranin A expression in normal and malignant human tissues J Clin Invest. 1988 Aug;82(2):686-90.
6: Nolan EM, Cheung TC, Burton DW, Deftos LJ. Identification and characterization of a neuroendocrine-specific 5′-regulatory region of the human chromogranin A gene Endocrinology. 1995 Dec;136(12):5632-8.
7: Degorce F, Goumon Y, Jacquemart L, Vidaud C, Bellanger L, Pons-Anicet D, Seguin P, Metz-Boutigue MH, Aunis D. A new human chromogranin A (CgA) immunoradiometric assay involving monoclonal antibodies raised against the unprocessed central domain (145-245) Br J Cancer. 1999 Jan;79(1):65-71.
8: Subramanian L, Khan AA, Allu PKR, Kiranmayi M, Sahu BS, Sharma S, Khullar M, Mullasari AS, Mahapatra NR. A haplotype variant of the human chromogranin A gene (CHGA) promoter increases CHGA expression and the risk for cardiometabolic disorders J Biol Chem. 2017 Aug 25;292(34):13970-13985.
9: Biswas N, Vaingankar SM, Mahata M, Das M, Gayen JR, Taupenot L, Torpey JW, O’Connor DT, Mahata SK. Proteolytic cleavage of human chromogranin a containing naturally occurring catestatin variants: differential processing at catestatin region by plasmin Endocrinology. 2008 Feb;149(2):749-57.
10: Inomoto C, Osamura RY. Formation of secretory granules by chromogranins Med Mol Morphol. 2009 Dec;42(4):201-3.

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