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PLTX-II Peptide (Highly Pure)

$595.00

Catalog number: MDP0671 (10 ug)
Name: Ala-Asp-Cys-Ser-Ala-Thr-Gly-Asp-Thr-Cys-Asp-His-Thr-Lys-Lys-Cys-Cys-Asp-Asp-Cys-Tyr-Thr-Cys-Arg-Cys-Gly-Thr-Pro-Trp-Gly-Ala-Asn-Cys-Arg-Cys-Asp-Tyr-Tyr-Lys-Ala-Arg-Cys-Asp-Thr(Palmitoyl)-NH2 (Disulfide bonds undetermined)
Other name(s): PLTX-II
Molecular Formula: C208H313N61O70S10
Molecular Mass: 5108.7
Storage Temperature: -20 C

In stock

SKU: MDP0671 Category: Tag:

Description

PLTX-II Peptide

Price per 10 ug: $595
Catalog number: MDP0671
Name: Ala-Asp-Cys-Ser-Ala-Thr-Gly-Asp-Thr-Cys-Asp-His-Thr-Lys-Lys-Cys-Cys-Asp-Asp-Cys-Tyr-Thr-Cys-Arg-Cys-Gly-Thr-Pro-Trp-Gly-Ala-Asn-Cys-Arg-Cys-Asp-Tyr-Tyr-Lys-Ala-Arg-Cys-Asp-Thr(Palmitoyl)-NH2 (Disulfide bonds undetermined)
Other name(s): PLTX-II
Molecular Formula: C208H313N61O70S10
Molecular Mass: 5108.7
Storage Temperature: -20 C
Indication for Use:
This product if for Research Use Only (RUO). This product is not for administration to humans or animals. This product is not for human or veterinary diagnostic or therapeutic use.

Safety:
User must review the Material Safety Data Sheet (MSDS) provided with this product. In addition, this product should not be ingested, inhaled, swallowed or put in contact with eyes, skin or clothes.

Products related to PLTX-II Peptide can be found here: Peptides

References:
1: Kimura T, Kubo T. Functional identification of a cloned squid presynaptic voltage-dependent calcium channel Neuroreport. 2002 Dec 20;13(18):2389-93.
2: Bódi J, Nishio H, Zhou Y, Branton WD, Kimura T, Sakakibara S. Synthesis of an O-palmitoylated 44-residue peptide amide (PLTX II) blocking presynaptic calcium channels in Drosophila Pept Res. 1995 Jul-Aug;8(4):228-35.
3: Jiang SA, Campusano JM, Su H, O’Dowd DK. Drosophila mushroom body Kenyon cells generate spontaneous calcium transients mediated by PLTX-sensitive calcium channels J Neurophysiol. 2005 Jul;94(1):491-500.
4: King GF. Modulation of insect Ca(v) channels by peptidic spider toxins Toxicon. 2007 Mar 15;49(4):513-30.
5: Branton WD, Rudnick MS, Zhou Y, Eccleston ED, Fields GB, Bowers LD. Fatty acylated toxin structure Nature. 1993 Oct 7;365(6446):496-7.
6: Hou J, Tamura T, Kidokoro Y. Delayed synaptic transmission in Drosophila cacophonynull embryos J Neurophysiol. 2008 Nov;100(5):2833-42.
7: Corzo G, Gilles N, Satake H, Villegas E, Dai L, Nakajima T, Haupt J. Distinct primary structures of the major peptide toxins from the venom of the spider Macrothele gigas that bind to sites 3 and 4 in the sodium channel FEBS Lett. 2003 Jul 17;547(1-3):43-50.
8: Kuromi H, Honda A, Kidokoro Y. Ca2+ influx through distinct routes controls exocytosis and endocytosis at drosophila presynaptic terminals Neuron. 2004 Jan 8;41(1):101-11.
9: Yan K, Haque AJ, Nandhakumar P, Bhatia A, Lee NS, Yoon YH, Yang H. Boosting electrochemical immunosensing performance by employing acetaminophen as a peroxidase substrate Biosens Bioelectron. 2020 Oct 1;165:112337.
10: Yoshihara M, Ueda A, Zhang D, Deitcher DL, Schwarz TL, Kidokoro Y. Selective effects of neuronal-synaptobrevin mutations on transmitter release evoked by sustained versus transient Ca2+ increases and by cAMP J Neurosci. 1999 Apr 1;19(7):2432-41.

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