Perlecan Antibody (Affinity Purified)


Catalog Number: B2010876 (0.1 mg)
Perlecan Antibody (Affinity Purified) is a highly pure affinity-purified antibody to low-density Heparan sulfate proteoglycans (HSPG, Perlecan). This product has been used as molecular tool for various biochemical studies. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Perlecan Antibody (Affinity Purified)
Catalog number: B2010876
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.1 mg
Molecular Weight or Concentration: na
Supplied as: Solution
Applications: molecular tool for various biochemical studies
Storage: -20°C
Keywords: Anti-Perlecan Monoclonal Antibody
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Tsiantoulas D, Eslami M, Obermayer G, Clement M, Smeets D, Mayer FJ, Kiss MG, Enders L, Weißer J, Göderle L, Lambert J, Frommlet F, Mueller A, Hendrikx T, Ozsvar-Kozma M, Porsch F, Willen L, Afonyushkin T, Murphy JE, Fogelstrand P, Donzé O, Pasterkamp G, Hoke M, Kubicek S, Jørgensen HF, Danchin N, Simon T, Scharnagl H, März W, Borén J, Hess H, Mallat Z, Schneider P, Binder CJ. APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans Nature. 2021 Sep;597(7874):92-96.
2: Khanna V, Kalscheuer S, Kirtane A, Zhang W, Panyam J. Perlecan-targeted nanoparticles for drug delivery to triple-negative breast cancer Future Drug Discov. 2019 Jul 1;1(1):FDD8.
3: Dieudé M, Cardinal H, Hébert MJ. Injury derived autoimmunity: Anti-perlecan/LG3 antibodies in transplantation Hum Immunol. 2019 Aug;80(8):608-613.
4: Tellman TV, Cruz LA, Grindel BJ, Farach-Carson MC. Cleavage of the Perlecan-Semaphorin 3A-Plexin A1-Neuropilin-1 (PSPN) Complex by Matrix Metalloproteinase 7/Matrilysin Triggers Prostate Cancer Cell Dyscohesion and Migration Int J Mol Sci. 2021 Mar 22;22(6):3218.
5: Joosten SA, van Dixhoorn MG, Borrias MC, Benediktsson H, van Veelen PA, van Kooten C, Paul LC. Antibody response against perlecan and collagen types IV and VI in chronic renal allograft rejection in the rat Am J Pathol. 2002 Apr;160(4):1301-10.
6: Zhang Q, Reed EF. The importance of non-HLA antibodies in transplantation Nat Rev Nephrol. 2016 Aug;12(8):484-95.
7: Kalscheuer S, Khanna V, Kim H, Li S, Sachdev D, DeCarlo A, Yang D, Panyam J. Discovery of HSPG2 (Perlecan) as a Therapeutic Target in Triple Negative Breast Cancer Sci Rep. 2019 Aug 28;9(1):12492.
8: Nickerson PW, Rush DN. Antibodies beyond HLA Am J Transplant. 2013 Apr;13(4):831-832.
9: Miller JD, Cummings J, Maresh GA, Walker DG, Castillo GM, Ngo C, Kimata K, Kinsella MG, Wight TN, Snow AD. Localization of perlecan (or a perlecan-related macromolecule) to isolated microglia in vitro and to microglia/macrophages following infusion of beta-amyloid protein into rodent hippocampus Glia. 1997 Oct;21(2):228-43.
10: Peng HB, Ali AA, Daggett DF, Rauvala H, Hassell JR, Smalheiser NR. The relationship between perlecan and dystroglycan and its implication in the formation of the neuromuscular junction Cell Adhes Commun. 1998 Sep;5(6):475-89.

Products Related to Perlecan Antibody (Affinity Purified): Antibodies

Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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