PAMP (Rat)

Product Description

PAMP (Rat)
Catalog number: MDP0663
CAS Number: 131580-10-4
Sequence: Ala-Arg-Leu-Asp-Thr-Ser-Ser-Gln-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH2
Amount: 500 ug
Molecular Weight: 2477.6 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20 °C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.

References:
1: Frank MG, Nguyen KH, Ball JB, Hopkins S, Kelley T, Baratta MV, Fleshner M, Maier SF. SARS-CoV-2 spike S1 subunit induces neuroinflammatory, microglial and behavioral sickness responses: Evidence of PAMP-like properties Brain Behav Immun. 2022 Feb;100:267-277.
2: Singh AK, Praharaj M, Lombardo KA, Yoshida T, Matoso A, Baras AS, Zhao L, Srikrishna G, Huang J, Prasad P, Powell JD, Kates M, McConkey D, Pardoll DM, Bishai WR, Bivalacqua TJ. Re-engineered BCG overexpressing cyclic di-AMP augments trained immunity and exhibits improved efficacy against bladder cancer Nat Commun. 2022 Feb 15;13(1):878.
3: Hu Y, Mai W, Chen L, Cao K, Zhang B, Zhang Z, Liu Y, Lou H, Duan S, Gao Z. mTOR-mediated metabolic reprogramming shapes distinct microglia functions in response to lipopolysaccharide and ATP Glia. 2020 May;68(5):1031-1045.
4: Engelmann C, Sheikh M, Sharma S, Kondo T, Loeffler-Wirth H, Zheng YB, Novelli S, Hall A, Kerbert AJC, Macnaughtan J, Mookerjee R, Habtesion A, Davies N, Ali T, Gupta S, Andreola F, Jalan R. Toll-like receptor 4 is a therapeutic target for prevention and treatment of liver failure J Hepatol. 2020 Jul;73(1):102-112.
5: Iwasaki H, Hirata Y, Iwashina M, Sato K, Marumo F. Specific binding sites for proadrenomedullin N-terminal 20 peptide (PAMP) in the rat Endocrinology. 1996 Jul;137(7):3045-50.
6: Rodrigues-Santos I, Kalil-Cutti B, Anselmo-Franci JA. Low Corticosterone Response to Stress in a Perimenopausal Rat Model Is Associated with the Hypoactivation of PaMP Region of the Paraventricular Nucleus and Can Be Corrected by Exogenous Progesterone Supplementation Neuroendocrinology. 2022;112(5):467-480.
7: Inatsu H, Sakata J, Shimokubo T, Kitani M, Nishizono M, Washimine H, Kitamura K, Kangawa K, Matsuo H, Eto T. Distribution and characterization of rat immunoreactive proadrenomedullin N-terminal 20 peptide (PAMP) and the augmented cardiac PAMP in spontaneously hypertensive rat Biochem Mol Biol Int. 1996 Feb;38(2):365-72.
8: Rebuffat P, Gottardo L, Malendowicz LK, Neri G, Nussdorfer GG. Proadrenomedullin N-terminal 20 peptide (PAMP) enhances proliferation of rat zona glomerulosa cells by activating MAPK cascade Peptides. 2001 Nov;22(11):1909-12.
9: Guo D, Dang J, Yang H, Fan Y, Cheng J, Shi Y, Zhang X, Zou J. Simultaneous determination of four flavonoids in rat plasma after oral administration of Malus hupehensis (Pamp.) Rehd. extracts by UPLC-MS/MS and its application to a pharmacokinetics study J Pharm Biomed Anal. 2020 Jan 5;177:112869.
10: Thomson LM, Kapas S, Hinson JP. Proadrenomedullin N-terminal 20 peptide (PAMP) stimulates aldosterone secretion by the intact rat adrenal glomerulosa by a cAMP-dependent mechanism FEBS Lett. 1998 Jul 31;432(1-2):37-9.

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