Octakis(6-Deoxy-6-(2-((ethylcarboxy)ethyl)thio))-gamma-cyclodextrin

Product Description

Octakis(6-Deoxy-6-(2-((ethylcarboxy)ethyl)thio))-gamma-cyclodextrin
Catalog number: B2027397
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 mg
Molecular Weight or Concentration: 2227
Supplied as: Chemicals
Storage: −80°C
Keywords: Octakis(6-deoxy-6-(2-carboxyethylthio))-gamma-cyclodextrin octaethyl ester, Sugammadex ethyl ester, Octakis(6-Deoxy-6-(2-((ethylcarboxy)ethyl)thio))-γ-cyclodextrin

References:
1. Bom, A., Bradley, M., Cameron, K., Clark, J. K., Van Egmond, J., Feilden, H., … & Zhang, M. Q. (2002). A novel concept of reversing neuromuscular block: chemical encapsulation of rocuronium bromide by a cyclodextrin-based synthetic host. Angewandte Chemie International Edition, 41(14), 2656-2660.
2. Gijsenbergh, F., Ramael, S., Houwing, N., & van Iersel, T. (2005). First human exposure of Org 25969, a novel agent to reverse the action of rocuronium bromide. Anesthesiology, 103(4), 695-703.
3. Shields, M. O., Giovannelli, M., Mirakhur, R. K., Moppett, I., Adams, J., & Hermens, Y. (2006). Org 25969 (sugammadex) facilitates rapid recovery from rocuronium-induced neuromuscular block. British Journal of Anaesthesia, 96(1), 36-43.
4. Welliver, M. (2006). Sugammadex: A selective relaxant binding agent. AANA Journal, 74(5), 357-363.
5. Nicholson, W. T., Sprung, J., & Jankowski, C. J. (2007). Sugammadex: a novel agent for the reversal of neuromuscular blockade. Pharmacotherapy, 27(8), 1181-1188.
6. Sacan, O., White, P. F., Tufanogullari, B., & Klein, K. (2007). Sugammadex reversal of rocuronium-induced neuromuscular blockade: a comparison with neostigmine-glycopyrrolate and edrophonium-atropine. Anesthesia & Analgesia, 104(3), 569-574.
7. Suy, K., Morias, K., De Boer, H. D., Van Egmond, J., Heeringa, M., & Booij, L. H. (2007). Effective reversal of moderate rocuronium-or vecuronium-induced neuromuscular block with sugammadex, a selective relaxant binding agent. Anesthesiology, 106(2), 283-288.
8. De Boer, H. D., Driessen, J. J., Marcus, M. A., Kerkkamp, H., Heeringa, M., & Klimalten, M. (2007). Reversal of rocuronium-induced profound neuromuscular block by sugammadex: a multicenter, dose-finding study. Anesthesiology, 107(2), 239-244.
9. Yang, L. P., & Keam, S. J. (2009). Sugammadex: a review of its use in anaesthetic practice. Drugs, 69(7), 919-942.
10. Mirakhur, R. K. (2009). Sugammadex in clinical practice. Anaesthesia, 64(s1), 45-54.
Octakis(6-Deoxy-6-(2-((ethylcarboxy)ethyl)thio))-gamma-cyclodextrin

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