Nephrin Antibody (Human Polyclonal)

Description

Nephrin Antibody (Human Polyclonal)
Catalog number: B2010424
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 uL
Molecular Weight or Concentration: 150 kDa
Supplied as: Liquid
Appearance: Liquid Solution
Applications: Rabbit polyclonal antibody to human Nephrin (NPHS1, NPHN).
Storage: -20C
Keywords: Nephrin, Renal glomerulus-specific cell adhesion receptor
Grade: Biotechnology grade. All solid components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Dlugos CP, Picciotto C, Lepa C, Krakow M, Stöber A, Eddy ML, Weide T,
Jeibmann A, P Krahn M, Van Marck V, Klingauf J, Ricker A, Wedlich-Söldner R,
Pavenstädt H, Klämbt C, George B. Nephrin Signaling Results in Integrin
β1 Activation. J Am Soc Nephrol. 2019 Jun;30(6):1006-1019.

2: Denhez B, Geraldes P. Regulation of Nephrin Phosphorylation in Diabetes and
Chronic Kidney Injury. Adv Exp Med Biol. 2017;966:149-161.

3: Verma R, Venkatareddy M, Kalinowski A, Li T, Kukla J, Mollin A, Cara-Fuentes
G, Patel SR, Garg P. Nephrin is necessary for podocyte recovery following injury
in an adult mature glomerulus. PLoS One. 2018 Jun 20;13(6):e0198013.

4: Akankwasa G, Jianhua L, Guixue C, Changjuan A, Xiaosong Q. Urine markers of
podocyte dysfunction: a review of podocalyxin and nephrin in selected glomerular
diseases. Biomark Med. 2018 Aug;12(8):927-935.

5: Kim S, Kalappurakkal JM, Mayor S, Rosen MK. Phosphorylation of nephrin
induces phase separated domains that move through actomyosin contraction. Mol
Biol Cell. 2019 Nov 15;30(24):2996-3012.

6: Hauser PV, Collino F, Bussolati B, Camussi G. Nephrin and endothelial injury.
Curr Opin Nephrol Hypertens. 2009 Jan;18(1):3-8.

7: Welsh GI, Saleem MA. Nephrin-signature molecule of the glomerular podocyte? J
Pathol. 2010 Feb;220(3):328-37.

8: Li X, He JC. An update: the role of Nephrin inside and outside the kidney.
Sci China Life Sci. 2015 Jul;58(7):649-57.

9: Chen J, Li G, Wang S, Hu X, Sun Y, Dai X, Bai Z, Pan J, Li X, Wang J, Li Y.
Urinary Nephrin as a Biomarker of Glomerular Maturation and Injury Is Associated
with Acute Kidney Injury and Mortality in Critically Ill Neonates. Neonatology.
2019;116(1):58-66.
10: Martin CE, New LA, Phippen NJ, Keyvani Chahi A, Mitro AE, Takano T, Pawson
T, Blasutig IM, Jones N. Multivalent nephrin-Nck interactions define a threshold
for clustering and tyrosine-dependent nephrin endocytosis. J Cell Sci. 2020 Feb
24;133(4):jcs236877.

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