Native Porcine Mucin 2

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Native Porcine Mucin 2
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Native Porcine Mucin 2

Original price was: $1,995.00.Current price is: $995.00.

Catalog Number: B2027150 (100 ug)
Native Porcine Mucin 2 is a highly glycosylated, gel-forming oligomeric protein isolated from porcine sources that serves as the central structural component of the protective mucosal barrier. It features a specialized core domain rich in threonine and proline residues modified by extensive O-linked glycans, which are critical for maintaining hydration, surface lubrication, and selective permeability. This biotechnology product is purified for research applications, including cell culture models, immunological assays, and studies on host-microbe interactions or pathogen defense. Custom bulk amounts of this product are available upon request.

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Product Description

5/5 - (1 vote)

Native Porcine Mucin 2
Catalog number: B2027150
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: NA
Supplied as: Solution
Storage: −20°C
Keywords: MUC2, MLP, SMUC, Oligomeric Mucus/Gel-Forming, Mucin 2 Intestinal/Tracheal, Intestinal mucin-2

References:
1. Wood EN. An apparently new syndrome of porcine epidemic diarrhoea. Vet Rec. 1977;102(11):243.
2. Pelaseyed T, Bergström JH, Gustafsson JK, et al. The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system. Immunol Rev. 2014;260(1):8-20.
3. Johansson MEV, Gustafsson JK, Holmén-Larsson J, et al. Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis. Gut. 2014;63(2):281-291.
4. Ermund A, Schütte A, Johansson MEV, Gustafsson JK, Hansson GC. Studies of mucus in mouse stomach, small intestine, and colon. I. Gastrointestinal mucus layers have different properties depending on location as well as over time. Am J Physiol Gastrointest Liver Physiol. 2013;305(5):G341-G347.
5. Basbaum C, Lemjabbar H, Longphre M, Li D, Gensh E, McNamara N. Control of mucin transcription by diverse injury-induced signaling pathways. Am J Respir Crit Care Med. 2002;166(12 Pt 2):S53-S56.
6. Liu Y, Yu XJ, Zhao JX, Zhang H, Zhai QX, Chen W. The role of MUC2 mucin in intestinal homeostasis and the impact of dietary components on MUC2 expression. Int J Biol Macromol. 2020;164:2549-2559.
7. Wang N, Tang XC. Research progress of mucin-2 and intestinal mucosal barrier damage. Basic Clin Med. 2018;38(4):553-557.
8. Yang Z, Liao SF. Physiological effects of dietary amino acids on gut health and functions of swine. Front Vet Sci. 2019;6:169.
9. Bansil R, Turner BS. Mucin structure, gating, and cell signalling. Curr Opin Colloid Interface Sci. 2006;11(2-3):164-170.
10. Thornton DJ, Rousseau K, Khan MA. Structure and function of the polymeric mucins in airways mucus. Annu Rev Physiol. 2008;70:459-486.
Native Porcine Mucin 2

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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