N-acetyl-D-Mannosamine (Highly Pure)


Catalog Number: B2013152 (25 mg)
N-acetyl-D-Mannosamine (Highly Pure) is a high quality ManNAc compound that reverses hyposialylation and improves glomerular integrity. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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N-acetyl-D-Mannosamine (Highly Pure)
Catalog number: B2013152
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 25 mg
Molecular Weight or Concentration: 221.2 g/mol
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: ManNAc
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Hadfield AF, Mella SL, Sartorelli AC. N-acetyl-D-mannosamine analogues as potential inhibitors of sialic acid biosynthesis J Pharm Sci. 1983 Jul;72(7):748-51.
2: Nagasawa M, Shimozawa A, Mogi K, Kikusui T. N-acetyl-D-mannosamine treatment alleviates age-related decline in place-learning ability in dogs J Vet Med Sci. 2014 May;76(5):757-61.
3: Lichtenthaler FW. 2-Oxoglycosyl (“ulosyl”) and 2-oximinoglycosyl bromides: versatile donors for the expedient assembly of oligosaccharides with β-D-mannose, β-L-rhamnose, N-acetyl-β-D-mannosamine, and N-acetyl-β-D-mannosaminuronic acid units Chem Rev. 2011 Sep 14;111(9):5569-609.
4: Pampa KJ, Lokanath NK, Girish TU, Kunishima N, Rai VR. Crystal structure of product-bound complex of UDP-N-acetyl-d-mannosamine dehydrogenase from Pyrococcus horikoshii OT3 Biochem Biophys Res Commun. 2014 Oct 24;453(3):662-7.
5: COMB DG, ROSEMAN S. Enzymic synthesis of N-acetyl-D-mannosamine Biochim Biophys Acta. 1958 Sep;29(3):653-4.
6: Kawamura T, Kimura M, Yamamori S, Ito E. Enzymatic formation of uridine diphosphate N-acetyl-D-mannosamine_ J Biol Chem. 1978 May 25;253(10):3595-601.
7: Revilla-Nuin B, Reglero A, Ferrero MA, Rodríguez-Aparicio LB. Uptake of N-acetyl-D-mannosamine_: an essential intermediate in polysialic acid biosynthesis by Escherichia coli K92 FEBS Lett. 1999 Apr 23;449(2-3):183-6.
8: Amir SM, Barker SA, Butt WR, Crooke AC, Davies AG. Administration of N-acetyl-D-mannosamine_ to mammals Nature. 1966 Aug 27;211(5052):976-7.
9: Kawamura T, Ishimoto N, Ito E. UDP-N-acetyl-D-mannosamine dehydrogenase from Escherichia coli Methods Enzymol. 1982;83:519-22.
10: Taniguchi S, Kuwahara M, Ito K. Chronic administration of N-acetyl-D-mannosamine improves age-associated impairment of long-term potentiation in the senescence-accelerated mouse Neurosci Lett. 2015 Jun 26;598:41-6.

Products Related to N-acetyl-D-Mannosamine (Highly Pure) can be found at Carbohydrates

Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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