Mycophenolic Acid (High Purity)

Description

Mycophenolic Acid (High Purity)
Catalog number: B2010457
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 mg
Molecular Weight or Concentration: 320.34 g/mol
Supplied as: Powder
Appearance: Powder
Applications: highly pure (≥98%) Mycophenolic acid from Penicillium brevicompactum.
Storage: 2-8°C
Keywords: 6-(1,3-Dihydro-7-hydroxy-5-methoxy-4-methyl-1-oxoisobenzofuran-6-yl)-4-methyl-4-hexanoic acid, 6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid, NSC 129185
Grade: Biotechnology grade. All solid components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Dasgupta A. Therapeutic Drug Monitoring of Mycophenolic Acid. Adv Clin Chem.
2016;76:165-84.

2: Strathie Page SJ, Tait CP. Mycophenolic acid in dermatology a century after
its discovery. Australas J Dermatol. 2015 Feb;56(1):77-83.

3: Song X, Tu R, Mei X, Wu S, Lan B, Zhang L, Luo X, Liu J, Luo M. A
mycophenolic_acid derivative from the fungus Penicillium sp. SCSIO
sof101. Nat Prod Res. 2020 May;34(9):1206-1212.

4: Garg U, Munar A, Frazee C. Determination of Mycophenolic Acid and
Mycophenolic_Acid Glucuronide Using Liquid Chromatography Tandem Mass
Spectrometry (LC/MS/MS). Curr Protoc Toxicol. 2018 Feb 21;75:18.21.1-18.21.8.

5: Anand S, Srivastava P. Optimization Strategies for Purification of
Mycophenolic_Acid Produced by Penicillium brevicompactum. Appl Biochem
Biotechnol. 2020 Jun;191(2):867-880.

6: Honarbakhsh N, Rouini MR, Lesan-Pezeshki M, Javadi MR, Karimzadeh I, Mohebbi
N, Gholami K. Mycophenolic_Acid pharmacokinetics early after kidney transplant.
Exp Clin Transplant. 2013 Apr;11(2):112-7.

7: Bolin P Jr, Gohh R, Kandaswamy R, Shihab FS, Wiland A, Akhlaghi F, Melancon
K. Mycophenolic_acid in kidney transplant patients with diabetes mellitus: does
the formulation matter? Transplant Rev (Orlando). 2011 Jul;25(3):117-23.

8: Shaw LM, Nowak I. Mycophenolic_acid: measurement and relationship to
pharmacologic effects. Ther Drug Monit. 1995 Dec;17(6):685-9.

9: Cholewinski G, Malachowska-Ugarte M, Dzierzbicka K. The chemistry of
mycophenolic_acid synthesis and modifications towards desired biological
activity. Curr Med Chem. 2010;17(18):1926-41.

10: Kaplan B. Mycophenolic_acid trough level monitoring in solid organ
transplant recipients treated with mycophenolate mofetil: association with
clinical outcome. Curr Med Res Opin. 2006 Dec;22(12):2355-64.
11: Siebert A, Wysocka M, Krawczyk B, Cholewiński G, Rachoń J. Synthesis and
antimicrobial activity of amino acid and peptide derivatives of mycophenolic
acid. Eur J Med Chem. 2018 Jan 1;143:646-655.

Products Related to Mycophenolic Acid (High Purity) : Chemicals