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Myc Proto-Oncogene Protein (c-Myc) Monoclonal Antibody

Original price was: $2,195.00.Current price is: $1,095.00.

Catalog Number: B2017091 (50 ug)
Myc Proto-Oncogene Protein (c-Myc) Monoclonal Antibody is a high quality monoclonal antibody that specifically targets the c-Myc protein. The c-Myc protein is a transcription factor that plays a key role in regulating cell growth, proliferation, and differentiation. This antibody, produced by the 9E10 clone, is commonly used in research to detect and study the expression of c-Myc protein in cells and tissues. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

5/5 - (2 votes)

Myc Proto-Oncogene Protein (c-Myc) Monoclonal Antibody
Catalog number: B2017091
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 ug
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -20℃
Keywords: c-Myc
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Molyneux EM, Rochford R, Griffin B, Newton R, Jackson G, Menon G, Harrison CJ, Israels T, Bailey S. Burkitt’s lymphoma Lancet. 2012 Mar 31;379(9822):1234-44.
2: Pillow TH, Adhikari P, Blake RA, Chen J, Del Rosario G, Deshmukh G, Figueroa I, Gascoigne KE, Kamath AV, Kaufman S, Kleinheinz T, Kozak KR, Latifi B, Leipold DD, Sing Li C, Li R, Mulvihill MM, O’Donohue A, Rowntree RK, Sadowsky JD, Wai J, Wang X, Wu C, Xu Z, Yao H, Yu SF, Zhang D, Zang R, Zhang H, Zhou H, Zhu X, Dragovich PS. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity ChemMedChem. 2020 Jan 7;15(1):17-25.
3: Ennishi D, Jiang A, Boyle M, Collinge B, Grande BM, Ben-Neriah S, Rushton C, Tang J, Thomas N, Slack GW, Farinha P, Takata K, Miyata-Takata T, Craig J, Mottok A, Meissner B, Saberi S, Bashashati A, Villa D, Savage KJ, Sehn LH, Kridel R, Mungall AJ, Marra MA, Shah SP, Steidl C, Connors JM, Gascoyne RD, Morin RD, Scott DW. Double-Hit Gene Expression Signature Defines a Distinct Subgroup of Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma J Clin Oncol. 2019 Jan 20;37(3):190-201.
4: Daniel CJ, Sun XX, Chen Y, Zhang X, Dai MS, Sears RC. Detection of Post-translational Modifications on MYC Methods Mol Biol. 2021;2318:69-85.
5: Evan GI, Lewis GK, Ramsay G, Bishop JM. Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product Mol Cell Biol. 1985 Dec;5(12):3610-6.
6: Siegel J, Brandner G, Hess RD. Cross-reactivity of the monoclonal antibody 9E10 with murine c-MYC Int J Oncol. 1998 Dec;13(6):1259-62.
7: Royds JA, Sharrard RM, Parsons MA, Lawry J, Rees R, Cottam D, Wagner B, Rennie IG. C-myc oncogene expression in ocular melanomas Graefes Arch Clin Exp Ophthalmol. 1992;230(4):366-71.
8: Thieblemont C, Bernard S, Meignan M, Molina T. Optimizing initial therapy in DLBCL Best Pract Res Clin Haematol. 2018 Sep;31(3):199-208.
9: Sikora K, Chan S, Evan G, Gabra H, Markham N, Stewart J, Watson J. c-myc oncogene expression in colorectal cancer Cancer. 1987 Apr 1;59(7):1289-95.
10: Schüchner S, Behm C, Mudrak I, Ogris E. The Myc tag monoclonal antibody 9E10 displays highly variable epitope recognition dependent on neighboring sequence context Sci Signal. 2020 Jan 28;13(616):eaax9730.

Products Related to Myc Proto-Oncogene Protein (c-Myc) Monoclonal Antibody can be found at Antibodies

Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (2 votes)

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