(+)-MK 801 Maleate (High Purity)

Product Description

(+)-MK 801 Maleate (High Purity)
Catalog number: B2010947
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 337.4 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: (5S,10R)-5-Methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene Maleate, (5R,10S)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]-cyclohepten-5-10-imine, NMDA Antagonist I
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Tran S, Muraleetharan A, Fulcher N, Chatterjee D, Gerlai R. MK-801 increases locomotor activity in a context-dependent manner in zebrafish Behav Brain Res. 2016 Jan 1;296:26-29.
2: Jacobsen ME, Barros M, Maior RS. MK-801 reduces sensitivity to Müller-Lyer’s illusion in capuchin monkeys Behav Brain Res. 2017 Jan 1;316:54-58.
3: Zhang Y, Laster MJ, Eger EI 2nd, Sharma M, Sonner JM. Lidocaine, MK-801, and MAC Anesth Analg. 2007 May;104(5):1098-102, tables of contents.
4: Vardhan Reddy KH, Yen-Pon E, Cohen-Kaminsky S, Messaoudi S, Alami M. Convergent Strategy to Dizocilpine MK-801 and Derivatives J Org Chem. 2018 Apr 6;83(7):4264-4269.
5: Furuie H, Yamada K, Ichitani Y. MK-801-induced and scopolamine-induced hyperactivity in rats neonatally treated chronically with MK-801 Behav Pharmacol. 2013 Dec;24(8):678-83.
6: Cui X, Lefevre E, Turner KM, Coelho CM, Alexander S, Burne TH, Eyles DW. MK-801-induced behavioural sensitisation alters dopamine release and turnover in rat prefrontal cortex Psychopharmacology (Berl). 2015 Feb;232(3):509-17.
7: Saganová K, Marsala M. Intrathecal administration of dizocilpine maleate (MK-801) attenuates ischemic damage in the rabbit spinal cord Exp Neurol. 1994 Dec;130(2):337-43.
8: Traverso LM, Ruiz G, De la Casa LG. MK-801 induces a low intensity conditioned taste aversion Pharmacol Biochem Behav. 2012 Jan;100(3):645-51.
9: Chan M, Austen JM, Eacott MJ, Easton A, Sanderson DJ. The NMDA receptor antagonist MK-801 fails to impair long-term recognition memory in mice when the state-dependency of memory is controlled Neurobiol Learn Mem. 2019 May;161:57-62.
10: Wąsik A, Białoń M, Jantas D, Żarnowska M. The Impact of the Combined Administration of 1MeTIQ and MK-801 on Cell Viability, Oxidative Stress Markers, and Glutamate Release in the Rat Hippocampus Neurotox Res. 2021 Dec;39(6):1747-1761.

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