Human Maspin (Highly Pure, Recombinant)


Catalog Number: B2010274 (10 ug)
Maspin (Human, Recombinant) is a high quality research product used as highly pure human Maspin (expressed in E. coli). This 42 kDa protein has been shown to inhibit the invasion and motility of mammary tumors. Custom bulk orders of this product are available upon request.

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SKU: B2010274 Categories: ,


Human Maspin (Highly Pure, Recombinant)
Catalog number: B2010274
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized powder
Appearance: Powder
Applications: highly pure human Maspin (expressed in E. coli). This 42 kDa protein has been shown to inhibit the invasion and motility of mammary tumors.
Storage: -20C
Keywords: rHuMaspin; Serpin B5; PI-5
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through0.22 um.

1: Bernardo MM, Dzinic SH, Matta MJ, Dean I, Saker L, Sheng S. The Opportunity
of Precision Medicine for Breast Cancer With Context-Sensitive Tumor Suppressor
Maspin. J Cell Biochem. 2017 Jul;118(7):1639-1647.

2: Mahajan N, Hoover B, Rajendram M, Shi HY, Kawasaki K, Weibel DB, Zhang M.
Maspin binds to cardiolipin in mitochondria and triggers apoptosis. FASEB J.
2019 May;33(5):6354-6364.

3: Zhang Y, Liu H, Shi X, Qiao F, Zeng W, Feng L, Deng D, Liu H, Wu Y. Maspin
impairs the function of endothelial cells: an implying pathway of preeclampsia.
BMC Pregnancy Childbirth. 2017 Sep 29;17(1):328.

4: Dzinic SH, Bernardo MM, Oliveira DS, Wahba M, Sakr W, Sheng S. Tumor
suppressor maspin as a modulator of host immune response to cancer. Bosn J Basic
Med Sci. 2015 Oct 25;15(4):1-6.

5: Wang N, Chang LL. Maspin suppresses cell invasion and migration in gastric
cancer through inhibiting EMT and angiogenesis via ITGB1/FAK pathway. Hum Cell.
2020 Jul;33(3):663-675.

6: Shi X, Liu Q, Liu H, Deng D, Qiao F, Wu Y. Effects of shRNA Targeting Maspin
on the Invasion of Extravillous Trophoblast Cell. Am J Perinatol. 2017

7: Baghel K, Kazmi HR, Chandra A, Raj S, Srivastava RN. Significance of
methylation status of MASPIN gene and its protein expression in prognosis of
gallbladder cancer. Asia Pac J Clin Oncol. 2019 Oct;15(5):e120-e125.

8: Wang Y, Sun L, Song Z, Wang D, Bao Y, Li Y. Maspin inhibits macrophage
phagocytosis and enhances inflammatory cytokine production via activation of NF-
κB signaling. Mol Immunol. 2017 Feb;82:94-103.

9: Helal DS, El-Guindy DM. Maspin expression and subcellular localization in
invasive ductal carcinoma of the breast: Prognostic significance and relation to
microvessel density. J Egypt Natl Canc Inst. 2017 Dec;29(4):177-183.
10: Gurzu S, Kadar Z, Sugimura H, Orlowska J, Bara T, Bara T Jr, Szederjesi J,
Jung I. Maspin-related Orchestration of Aggressiveness of Gastric Cancer. Appl
Immunohistochem Mol Morphol. 2016 May-Jun;24(5):326-36.

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