Human Maspin (Highly Pure, Recombinant)

Product Description

Human Maspin (Highly Pure, Recombinant)
Catalog number: B2010274
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized powder
Appearance: Powder
Applications: highly pure human Maspin (expressed in E. coli). This 42 kDa protein has been shown to inhibit the invasion and motility of mammary tumors.
Storage: -20C
Keywords: rHuMaspin; Serpin B5; PI-5
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through0.22 um.

References:
1: Bernardo MM, Dzinic SH, Matta MJ, Dean I, Saker L, Sheng S. The Opportunity
of Precision Medicine for Breast Cancer With Context-Sensitive Tumor Suppressor
Maspin. J Cell Biochem. 2017 Jul;118(7):1639-1647.

2: Mahajan N, Hoover B, Rajendram M, Shi HY, Kawasaki K, Weibel DB, Zhang M.
Maspin binds to cardiolipin in mitochondria and triggers apoptosis. FASEB J.
2019 May;33(5):6354-6364.

3: Zhang Y, Liu H, Shi X, Qiao F, Zeng W, Feng L, Deng D, Liu H, Wu Y. Maspin
impairs the function of endothelial cells: an implying pathway of preeclampsia.
BMC Pregnancy Childbirth. 2017 Sep 29;17(1):328.

4: Dzinic SH, Bernardo MM, Oliveira DS, Wahba M, Sakr W, Sheng S. Tumor
suppressor maspin as a modulator of host immune response to cancer. Bosn J Basic
Med Sci. 2015 Oct 25;15(4):1-6.

5: Wang N, Chang LL. Maspin suppresses cell invasion and migration in gastric
cancer through inhibiting EMT and angiogenesis via ITGB1/FAK pathway. Hum Cell.
2020 Jul;33(3):663-675.

6: Shi X, Liu Q, Liu H, Deng D, Qiao F, Wu Y. Effects of shRNA Targeting Maspin
on the Invasion of Extravillous Trophoblast Cell. Am J Perinatol. 2017
Aug;34(10):966-973.

7: Baghel K, Kazmi HR, Chandra A, Raj S, Srivastava RN. Significance of
methylation status of MASPIN gene and its protein expression in prognosis of
gallbladder cancer. Asia Pac J Clin Oncol. 2019 Oct;15(5):e120-e125.

8: Wang Y, Sun L, Song Z, Wang D, Bao Y, Li Y. Maspin inhibits macrophage
phagocytosis and enhances inflammatory cytokine production via activation of NF-
κB signaling. Mol Immunol. 2017 Feb;82:94-103.

9: Helal DS, El-Guindy DM. Maspin expression and subcellular localization in
invasive ductal carcinoma of the breast: Prognostic significance and relation to
microvessel density. J Egypt Natl Canc Inst. 2017 Dec;29(4):177-183.
10: Gurzu S, Kadar Z, Sugimura H, Orlowska J, Bara T, Bara T Jr, Szederjesi J,
Jung I. Maspin-related Orchestration of Aggressiveness of Gastric Cancer. Appl
Immunohistochem Mol Morphol. 2016 May-Jun;24(5):326-36.

Products Related to Maspin (Human, Recombinant) : Proteins