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Lumican, Antibody

Original price was: $1,995.00.Current price is: $995.00.

Catalog Number: B2026972 (100 ug)
This antibody is used for the detection and study of the small leucine-rich proteoglycan lumican. Custom bulk amounts of this product are available upon request.

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SKU: B2026972 Category: Tag:

Product Description

5/5 - (2 votes)

Lumican, Antibody
Catalog number: B2026972
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 0.1 mg/mL
Supplied as: Solution
Storage: −20°C
Keywords: LDC, SLRR2D, LUM, KSPG Lumican, Keratan Sulfate Proteoglycan Lumican, lumican proteoglycan

References:
1. Chakravarti S, Magnuson T, Lass JH, Jepsen KJ, LaMantia C, Carroll H. Lumican regulates collagen fibril assembly: skin fragility and corneal opacity in the absence of lumican. J Cell Biol. 1998;141(5):1277-86.
2. Shao H, Scott SG, Nakata C, Hamad AR, Chakravarti S. Extracellular matrix protein lumican promotes clearance and resolution of Pseudomonas aeruginosa keratitis in a mouse model. PLoS One. 2013;8(1):e54765.
3. Smith MM, Melrose J. Lumican, a multifunctional cell instructive biomarker proteoglycan has novel roles as a marker of the hypercoagulative state of long COVID disease. Int J Mol Sci. 2023;24(11):9345.
4. Mohammadzadeh N, Lunde IG, Andenæs K, Strand ME, Aronsen JM, Skrbic B, et al. The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload. Sci Rep. 2019;9(1):9206.
5. Wu F, Vij N, Roberts L, Lopez-Briones S, Joyce S, Chakravarti S. A novel role of the lumican core protein in bacterial lipopolysaccharide-induced innate immune response. J Biol Chem. 2007;282(36):26409-17.
6. Lee S, Bowrin K, Hamad AR, Chakravarti S. Extracellular matrix lumican deposited on the surface of neutrophils promotes migration by binding to beta2 integrin. Invest Ophthalmol Vis Sci. 2009;50(2):597-606.
7. Itoh Y, Sahni V, Itoh F, Zhang S, Itoh S, Solloway M, et al. Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations. Cell Rep. 2023;42(3):112260.
8. Ji J, Wu Z, Xu Y, Chen J, Wu S, Wu G, et al. Upregulated bone morphogenetic protein 5 enhances proliferation and epithelial-mesenchymal transition process in benign prostatic hyperplasia via BMP/Smad signaling pathway. Bioengineered. 2021;12(1):8191-203.
9. Nakata C, Shao H, Scott SG, Chakravarti S. Lumican-null mice show poor bacterial clearance and resolution of polymicrobial sepsis but elevated response to DNA. J Immunol. 2014;192(1):310-9.
10. Kawashima H, Hiratoko K, Watanabe N, Ogawa Y, Tsubota K. Lumican in carcinogenesis—revisited. Molecules. 2020;25(24):5953.
Lumican, Antibody

Products Related to Lumican, Antibody can be found at Antibodies

Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (2 votes)

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