Laurdan [6-Dodecanoyl-2-dimethylaminonaphthalene]

Product Description

Laurdan [6-Dodecanoyl-2-dimethylaminonaphthalene]
Catalog number: B2011101
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 353.6 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various chemical, biochemical and immunological applications
Storage: -20 °C
Keywords: Laurdan
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Owen DM, Rentero C, Magenau A, Abu-Siniyeh A, Gaus K. Quantitative imaging of membrane lipid order in cells and organisms Nat Protoc. 2011 Dec 8;7(1):24-35.
2: Hornum M , Kongsted J , Reinholdt P . Computational and photophysical characterization of a Laurdan malononitrile derivative Phys Chem Chem Phys. 2021 Apr 22;23(15):9139-9146.
3: Sezgin E, Kaiser HJ, Baumgart T, Schwille P, Simons K, Levental I. Elucidating membrane structure and protein behavior using giant plasma membrane vesicles Nat Protoc. 2012 May 3;7(6):1042-51.
4: Gunther G, Malacrida L, Jameson DM, Gratton E, Sánchez SA. LAURDAN since Weber: The Quest for Visualizing Membrane Heterogeneity Acc Chem Res. 2021 Feb 16;54(4):976-987.
5: Bagatolli LA. Monitoring Membrane Hydration with 2-(Dimethylamino)-6-Acylnaphtalenes Fluorescent Probes Subcell Biochem. 2015;71:105-25.
6: Malacrida L, Gratton E. LAURDAN fluorescence and phasor plots reveal the effects of a H(2)O(2) bolus in NIH-3T3 fibroblast membranes dynamics and hydration Free Radic Biol Med. 2018 Nov 20;128:144-156.
7: Marquezin CA, de Oliveira CMA, Vandresen F, Duarte EL, Lamy MT, Vequi-Suplicy CC. The interaction of a thiosemicarbazone derived from R – (+) – limonene with lipid membranes Chem Phys Lipids. 2021 Jan;234:105018.
8: Antollini SS, Barrantes FJ. Laurdan studies of membrane lipid-nicotinic acetylcholine receptor protein interactions Methods Mol Biol. 2007;400:531-42.
9: Gaus K, Zech T, Harder T. Visualizing membrane microdomains by Laurdan 2-photon microscopy Mol Membr Biol. 2006 Jan-Feb;23(1):41-8.
10: Pérez HA, Alarcón LM, Verde AR, Appignanesi GA, Giménez RE, Disalvo EA, Frías MA. Effect of cholesterol on the hydration properties of ester and ether lipid membrane interphases Biochim Biophys Acta Biomembr. 2021 Jan 1;1863(1):183489.

Products Related to Laurdan [6-Dodecanoyl-2-dimethylaminonaphthalene] can be found at Chemicals