L-Pyroglutamic Acid (Highly Pure)

Description

L-Pyroglutamic Acid (Highly Pure)
Catalog number: B2012384
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 mg
Molecular Weight or Concentration: 129.1 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: L-Glutamic Acid Lactam, (S)-5-Oxopyrrolidine-2-carboxylic Acid, (S)-2-Pyrrolidone-5-carboxylic Acid, H-Pyr-OH
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Chen XY, Gao ZH, Ye S. Bifunctional N-Heterocyclic Carbenes Derived from l-Pyroglutamic Acid and Their Applications in Enantioselective Organocatalysis Acc Chem Res. 2020 Mar 17;53(3):690-702.
2: Zhang Q, Li X, Yin X, Wang H, Fu C, Wang H, Li K, Li Y, Zhang X, Liang H, Li K, Li H, Qiu Y. Metabolomic profiling reveals serum L-pyroglutamic acid as a potential diagnostic biomarker for systemic lupus erythematosus Rheumatology (Oxford). 2021 Feb 1;60(2):598-606.
3: Wegener S, Kaufmann M, Kroh LW. Influence of l-pyroglutamic_acid on the color formation process of non-enzymatic browning reactions Food Chem. 2017 Oct 1;232:450-454.
4: Bilska K, Stuper-Szablewska K, Kulik T, Buśko M, Załuski D, Perkowski J. Resistance-Related l-Pyroglutamic Acid Affects the Biosynthesis of Trichothecenes and Phenylpropanoids by F. graminearum Sensu Stricto Toxins (Basel). 2018 Nov 24;10(12):492.
5: Beni M, Pellegrini-Giampietro DE, Moroni F. A new endogenous anxiolytic agent: L-pyroglutamic_acid Fundam Clin Pharmacol. 1988;2(2):77-82.
6: Maier JA, Pickering G, Giacomoni E, Cazzaniga A, Pellegrino P. Headaches and Magnesium: Mechanisms, Bioavailability, Therapeutic Efficacy and Potential Advantage of Magnesium Pidolate Nutrients. 2020 Aug 31;12(9):2660.
7: Gang FL, Zhu F, Li XT, Wei JL, Wu WJ, Zhang JW. Synthesis and bioactivities evaluation of l-pyroglutamic_acid analogues from natural product lead Bioorg Med Chem. 2018 Sep 1;26(16):4644-4649.
8: Xiao XQ, Liu GQ. L-pyroglutamic acid protects rat cortical neurons against sodium glutamate-induced injury Zhongguo Yao Li Xue Bao. 1999 Aug;20(8):733-6.
9: de Mello CF, De La Vega DD, Pizutti LT, Lopes FP, Rubin MA, Homerich JG, Melo CR, Somer JE, Souza DO, Wajner M. Neurochemical effects of L-pyroglutamic acid Neurochem Res. 1995 Dec;20(12):1437-41.
10: Mochizuki T, Todoroki K, Inoue K, Min JZ, Toyo’oka T. Isotopic variants of light and heavy L-pyroglutamic acid succinimidyl esters as the derivatization reagents for DL-amino acid chiral metabolomics identification by liquid chromatography and electrospray ionization mass spectrometry Anal Chim Acta. 2014 Feb 6;811:51-9.

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