Keratinocyte Growth Factor-2/FGF-10
Catalog Number: B2010316 (10 ug)
Keratinocyte Growth Factor-2/FGF-10 is a high quality research product used as highly pure Keratinocyte Growth Factor-2/FGF-10 expressed in E. coli. This protein acts as a heparin-binding protein that binds to FGF2 IIIb and FGFR1III-b receptors, promotes the growth, proliferation, and differentiation of epithelial cells. Custom bulk orders of this product are available upon request.
Keratinocyte Growth Factor-2/FGF-10
Catalog number: B2010316
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Applications: highly pure Keratinocyte Growth Factor-2/FGF-10 expressed in E. coli. This protein acts as a heparin-binding protein that binds to FGF2 IIIb and FGFR1III-b receptors, promotes the growth, proliferation, and differentiation of epithelial cells.
Keywords: rHuKGF-2/FGF-10; Fibroblast Growth Factor-10
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
1: Farajihaye Qazvini F, Samadi N, Saffari M, Emami-Razavi AN, Shirkoohi R.
Fibroblast growth factor-10 and epithelial-mesenchymal transition in colorectal
cancer. EXCLI J. 2019 Jul 17;18:530-539.
2: Kumtornrut C, Yamauchi T, Koike S, Aiba S, Yamasaki K. Androgens modulate
keratinocyte differentiation indirectly through enhancing growth factor
production from dermal fibroblasts. J Dermatol Sci. 2019 Mar;93(3):150-158.
3: Tong L, Zhou J, Rong L, Seeley EJ, Pan J, Zhu X, Liu J, Wang Q, Tang X, Qu J,
Bai C, Song Y. Fibroblast Growth Factor-10 (FGF-10) Mobilizes Lung-resident
Mesenchymal Stem Cells and Protects Against Acute Lung Injury. Sci Rep. 2016 Feb
4: Son YJ, Lee SE, Park YG, Jeong SG, Shin MY, Kim EY, Park SP. Fibroblast
Growth Factor 10 Enhances the Developmental Efficiency of Somatic Cell Nuclear
Transfer Embryos by Accelerating the Kinetics of Cleavage During In Vitro
Maturation. Cell Reprogram. 2018 Jun;20(3):196-204.
5: Jimenez PA, Rampy MA. Keratinocyte growth factor-2 accelerates wound healing
in incisional wounds. J Surg Res. 1999 Feb;81(2):238-42.
6: Han T, Chi M, Wang Y, Mei Y, Li Q, Yu M, Ma Q, Chen Y, Feng Z. Therapeutic
effects of fibroblast growth factor-10 on hyperoxia-induced bronchopulmonary
dysplasia in neonatal mice. Am J Transl Res. 2017 Aug 15;9(8):3528-3540.
7: Matsuike A, Ishiwata T, Watanabe M, Asano G. Expression of fibroblast growth
factor (FGF)-10 in human colorectal adenocarcinoma cells. J Nippon Med Sch. 2001
8: Kovacs D, Falchi M, Cardinali G, Raffa S, Carducci M, Cota C, Amantea A,
Torrisi MR, Picardo M. Immunohistochemical analysis of keratinocyte growth
factor and fibroblast growth factor 10 expression in psoriasis. Exp Dermatol.
9: Wang X, Zhou X, Ma J, Tian H, Jiao Y, Zhang R, Huang Z, Xiao J, Zhao B, Qian
H, Li X. Effects of keratinocyte growth factor-2 on corneal epithelial wound
healing in a rabbit model of carbon dioxide laser injury. Biol Pharm Bull.
10: Han DS, Li F, Holt L, Connolly K, Hubert M, Miceli R, Okoye Z, Santiago G,
Windle K, Wong E, Sartor RB. Keratinocyte growth factor-2 (FGF-10) promotes
healing of experimental small intestinal ulceration in rats. Am J Physiol
Gastrointest Liver Physiol. 2000 Nov;279(5):G1011-22.
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