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Interleukin-9 (Human, Recombinant)

$695.00 $495.00

Catalog Number: B2010313 (10 ug)
Interleukin-9 (Human, Recombinant) is a high quality research product used as highly pure Interleukin-9 (Human, Recombinant) expressed in CHO. This protein acts as an immunoregulatory cytokine produced by IL-2-activated Th2 lymphocytes. Custom bulk orders of this product are available upon request.

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SKU: B2010313 Categories: , ,

Description

Interleukin-9 (Human, Recombinant)
Catalog number: B2010313
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Interleukin-9 (Human, Recombinant) expressed in CHO. This protein acts as an immunoregulatory cytokine produced by IL-2-activated Th2 lymphocytes.
Storage: -20C
Keywords: rHuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Rauber S, Luber M, Weber S, Maul L, Soare A, Wohlfahrt T, Lin NY, Dietel K,
Bozec A, Herrmann M, Kaplan MH, Weigmann B, Zaiss MM, Fearon U, Veale DJ, Cañete
JD, Distler O, Rivellese F, Pitzalis C, Neurath MF, McKenzie ANJ, Wirtz S,
Schett G, Distler JHW, Ramming A. Resolution of inflammation by
interleukin-9-producing type 2 innate lymphoid cells. Nat Med. 2017
Aug;23(8):938-944.

2: Chakraborty S, Kubatzky KF, Mitra DK. An Update on Interleukin-9: From Its
Cellular Source and Signal Transduction to Its Role in Immunopathogenesis. Int J
Mol Sci. 2019 Apr 29;20(9):2113.

3: Gerlach K, Weigmann B. The dichotomous function of interleukin-9 in cancer
diseases. J Mol Med (Berl). 2019 Oct;97(10):1377-1383.

4: Matusiewicz K, Iwańczak B, Matusiewicz M. Th9 lymphocytes and functions of
interleukin 9 with the focus on IBD pathology. Adv Med Sci. 2018
Sep;63(2):278-284.

5: Zheng Y, He Y, Xiao M, Zhang W, Xia W, Hu H, Mao L, Liu A, Chen Z, Bai X, Li
Y. Interleukin 9 prevents immune thrombocytopenia in mice via JAK/STAT5
signaling. Exp Cell Res. 2020 Mar 1;388(1):111801.

6: Doshi A, Khamishon R, Rawson R, Duong L, Dohil L, Myers SJ, Bell B, Dohil R,
Newbury RO, Barrett KE, Kurten RC, Aceves SS. Interleukin 9 Alters Epithelial
Barrier and E-cadherin in Eosinophilic Esophagitis. J Pediatr Gastroenterol
Nutr. 2019 Feb;68(2):225-231.

7: Ye D, Wang Z, Xu Y, Ye J, Wang M, Liu J, Zhang J, Zhao M, Chen J, Wan J.
Interleukin-9 aggravates doxorubicin-induced cardiotoxicity by promoting
inflammation and apoptosis in mice. Life Sci. 2020 Aug 15;255:117844.

8: Wharton W, Kollhoff AL, Gangishetti U, Verble DD, Upadhya S, Zetterberg H,
Kumar V, Watts KD, Kippels AJ, Gearing M, Howell JC, Parker MW, Hu WT.
Interleukin 9 alterations linked to alzheimer disease in african americans. Ann
Neurol. 2019 Sep;86(3):407-418.
9: Park SM, Do-Thi VA, Lee JO, Lee H, Kim YS. Interleukin-9 Inhibits Lung
Metastasis of Melanoma through Stimulating Anti-Tumor M1 Macrophages. Mol Cells.
2020 May 31;43(5):479-490.

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